Biodistribution of polymer hydrogel capsules for the delivery of therapeutics

Tracey M Hinton, Paul Monaghan, Diane Green, Sander A A Kooijmans, Shuning Shi, Kerry Breheney, Mark L Tizard, Joseph Nicolazzo, Alexander N Zelikin, Kim Wark

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)


A key phase in the development of intelligently designed nanoparticle delivery vehicles for new therapeutic agents is to gain an understanding of their interaction with tissues and cells. We report a series of in vitro and in vivo experiments aimed at tracking a potential delivery vehicle for therapeutic agents, including vaccine peptides and drugs derived from poly(methacrylic acid) hydrogel capsules in certain organs and cell types.
Original languageEnglish
Pages (from-to)3251 - 3260
Number of pages10
JournalActa Biomaterialia
Issue number9
Publication statusPublished - 2012

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