Biochemical Genetics and Genomics of Insect Esterases

John Graham Oakeshott, Charles Claudianos, Peter M Campbell, Richard David Newcomb, Robyn J Russell

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review


Esterases have been a major part of insect biochemical research over the last 50 years. As an important component of insects? xenobiotic defence system, they have long been a focus for studies of chemical insecticide metabolism and resistance. Additionally, acetylcholinesterase (AChE) was a target for the early organophosphate (OP) and carbamate compounds. Other esterases have been implicated in the metabolism of specific hormones and pheromones and, consequently, in various aspects of insect development and behavior. Many esterases are easily scored by isozyme electrophoresis, with multiple isozymes and their high levels of genetic variation making them tractable, informative tools for a variety of biochemical and ecological genetic studies.
Original languageEnglish
Title of host publicationComprehensive Molecular Insect Science
EditorsLawrence I Gilbert, Kostas Iatrou, Sarjeeet S Gill
Place of PublicationNetherlands
Pages1 - 73
Number of pages73
ISBN (Print)9780444519245
Publication statusPublished - 2010

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