TY - JOUR
T1 - Binding of intimin from enteropathogenic Escherichia coli to lymphocytes and its functional consequences
AU - Gonçalves, Nathalie S.
AU - Hale, Christine
AU - Dougan, Gordon
AU - Frankel, Gad
AU - MacDonald, Thomas T.
PY - 2003/5/1
Y1 - 2003/5/1
N2 - Intimin-conjugated fluorescent beads bind to spleen CD4 T cells and Peyer's patch, mesenteric lymph node, and cecal follicle lymphocytes, with less binding to lamina propria T cells and intraepithelial lymphocytes. Intimin costimulates proliferation of spleen CD4 T cells and cells from organized lymphoid tissues but does not costimulate cells from the lamina propria of normal or inflamed colon.
AB - Intimin-conjugated fluorescent beads bind to spleen CD4 T cells and Peyer's patch, mesenteric lymph node, and cecal follicle lymphocytes, with less binding to lamina propria T cells and intraepithelial lymphocytes. Intimin costimulates proliferation of spleen CD4 T cells and cells from organized lymphoid tissues but does not costimulate cells from the lamina propria of normal or inflamed colon.
UR - http://www.scopus.com/inward/record.url?scp=0242416995&partnerID=8YFLogxK
U2 - 10.1128/IAI.71.5.2960-2965.2003
DO - 10.1128/IAI.71.5.2960-2965.2003
M3 - Article
C2 - 12704179
AN - SCOPUS:0242416995
VL - 71
SP - 2960
EP - 2965
JO - Infection and Immunity
JF - Infection and Immunity
SN - 1098-5522
IS - 5
ER -
