Benefits of pravastatin in older CAD patients

David Hunt; Peta Young; John Simes; Wendy Hague; Stewart Mann; Dwain Owensby; Geoffrey Lane; Andrew Tonkin

Benefits of pravastatin in older CAD patients

David Hunt, Peta Young, John Simes, Wendy Hague, Stewart Mann, Dwain Owensby, Geoffrey Lane, Andrew Tonkin

Research output: Contribution to journal › Review Article › Research › peer-review

Abstract

We examined the effect of pravastatin on cardiovascular outcomes in 3,514 patients ages 65 to 75 years with average cholesterol levels and previous acute coronary syndromes. The relative benefits were similar in these patients and those ages 31 to 64 years. The absolute benefit was greater and the numbers needed to treat to provide benefits were lower in older than in younger patients. Our data suggest pravastatin therapy is appropriate for older patients with previous myocardial infarctions or unstable angina and cholesterol levels of 155 to 271 mg/dL.

Original language	English
Pages (from-to)	34-37
Number of pages	4
Journal	Cardiology Review
Volume	19
Issue number	6
Publication status	Published - 2002
Externally published	Yes

Cite this

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title = "Benefits of pravastatin in older CAD patients",

abstract = "We examined the effect of pravastatin on cardiovascular outcomes in 3,514 patients ages 65 to 75 years with average cholesterol levels and previous acute coronary syndromes. The relative benefits were similar in these patients and those ages 31 to 64 years. The absolute benefit was greater and the numbers needed to treat to provide benefits were lower in older than in younger patients. Our data suggest pravastatin therapy is appropriate for older patients with previous myocardial infarctions or unstable angina and cholesterol levels of 155 to 271 mg/dL.",

author = "David Hunt and Peta Young and John Simes and Wendy Hague and Stewart Mann and Dwain Owensby and Geoffrey Lane and Andrew Tonkin",

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AU - Young, Peta

AU - Simes, John

AU - Hague, Wendy

AU - Mann, Stewart

AU - Owensby, Dwain

AU - Lane, Geoffrey

AU - Tonkin, Andrew

PY - 2002

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N2 - We examined the effect of pravastatin on cardiovascular outcomes in 3,514 patients ages 65 to 75 years with average cholesterol levels and previous acute coronary syndromes. The relative benefits were similar in these patients and those ages 31 to 64 years. The absolute benefit was greater and the numbers needed to treat to provide benefits were lower in older than in younger patients. Our data suggest pravastatin therapy is appropriate for older patients with previous myocardial infarctions or unstable angina and cholesterol levels of 155 to 271 mg/dL.

AB - We examined the effect of pravastatin on cardiovascular outcomes in 3,514 patients ages 65 to 75 years with average cholesterol levels and previous acute coronary syndromes. The relative benefits were similar in these patients and those ages 31 to 64 years. The absolute benefit was greater and the numbers needed to treat to provide benefits were lower in older than in younger patients. Our data suggest pravastatin therapy is appropriate for older patients with previous myocardial infarctions or unstable angina and cholesterol levels of 155 to 271 mg/dL.

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JO - Cardiology Review

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Benefits of pravastatin in older CAD patients

Abstract

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