Beneficial roles of honey polyphenols against some human degenerative diseases: A review

Md Sakib Hossen; Md Yousuf Ali; M. H.A. Jahurul; Mohamed M. Abdel-Daim; Siew Hua Gan; Md Ibrahim Khalil

doi:10.1016/j.pharep.2017.07.002

Beneficial roles of honey polyphenols against some human degenerative diseases: A review

Md Sakib Hossen, Md Yousuf Ali, M. H.A. Jahurul, Mohamed M. Abdel-Daim, Siew Hua Gan, Md Ibrahim Khalil

Research output: Contribution to journal › Review Article › Other › peer-review

163 Citations (Scopus)

Abstract

Honey contains many active constituents and antioxidants such as polyphenols. Polyphenols are phytochemicals, a generic term for the several thousand plant-based molecules with antioxidant properties. Many in vitro studies in human cell cultures as well as many animal studies confirm the protective effect of polyphenols on a number of diseases such as cardiovascular diseases (CVD), diabetes, cancer, neurodegenerative diseases, pulmonary diseases, liver diseases and so on. Nevertheless, it is challenging to identify the specific biological mechanism underlying individual polyphenols and to determine how polyphenols impact human health. To date, several studies have attempted to elucidate the molecular pathway for specific polyphenols acting against particular diseases. In this review, we report on the various polyphenols present in different types of honey according to their classification, source, and specific functions and discuss several of the honey polyphenols with the most therapeutic potential to exert an effect on the various pathologies of some major diseases including CVD, diabetes, cancer, and neurodegenerative diseases.

Original language	English
Pages (from-to)	1194-1205
Number of pages	12
Journal	Pharmacological Reports
Volume	69
Issue number	6
DOIs	https://doi.org/10.1016/j.pharep.2017.07.002
Publication status	Published - Dec 2017
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Antioxidants
Cancer
CVD
Diabetes
Honey
Neurodegenerative disease
Polyphenols

Access to Document

10.1016/j.pharep.2017.07.002

Cite this

@article{c488b1fcf4d541d8bdf7932da9109ae4,

title = "Beneficial roles of honey polyphenols against some human degenerative diseases: A review",

abstract = "Honey contains many active constituents and antioxidants such as polyphenols. Polyphenols are phytochemicals, a generic term for the several thousand plant-based molecules with antioxidant properties. Many in vitro studies in human cell cultures as well as many animal studies confirm the protective effect of polyphenols on a number of diseases such as cardiovascular diseases (CVD), diabetes, cancer, neurodegenerative diseases, pulmonary diseases, liver diseases and so on. Nevertheless, it is challenging to identify the specific biological mechanism underlying individual polyphenols and to determine how polyphenols impact human health. To date, several studies have attempted to elucidate the molecular pathway for specific polyphenols acting against particular diseases. In this review, we report on the various polyphenols present in different types of honey according to their classification, source, and specific functions and discuss several of the honey polyphenols with the most therapeutic potential to exert an effect on the various pathologies of some major diseases including CVD, diabetes, cancer, and neurodegenerative diseases.",

keywords = "Antioxidants, Cancer, CVD, Diabetes, Honey, Neurodegenerative disease, Polyphenols",

author = "Hossen, \{Md Sakib\} and Ali, \{Md Yousuf\} and Jahurul, \{M. H.A.\} and Abdel-Daim, \{Mohamed M.\} and Gan, \{Siew Hua\} and Khalil, \{Md Ibrahim\}",

note = "Funding Information: We are grateful to the National Science and Technology (NST) Fellowship ( 2014/2015 ) for providing financial support to Mr. Md. Sakib Hossen and Md. Yousuf Ali to pursue their MSc. We would like to acknowledge the Universiti Sains Malaysia (USM). Publisher Copyright: {\textcopyright} 2017 Institute of Pharmacology, Polish Academy of Sciences Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",

year = "2017",

month = dec,

doi = "10.1016/j.pharep.2017.07.002",

language = "English",

volume = "69",

pages = "1194--1205",

journal = "Pharmacological Reports",

issn = "1734-1140",

publisher = "Springer",

number = "6",

}

TY - JOUR

T1 - Beneficial roles of honey polyphenols against some human degenerative diseases

T2 - A review

AU - Hossen, Md Sakib

AU - Ali, Md Yousuf

AU - Jahurul, M. H.A.

AU - Abdel-Daim, Mohamed M.

AU - Gan, Siew Hua

AU - Khalil, Md Ibrahim

N1 - Funding Information: We are grateful to the National Science and Technology (NST) Fellowship ( 2014/2015 ) for providing financial support to Mr. Md. Sakib Hossen and Md. Yousuf Ali to pursue their MSc. We would like to acknowledge the Universiti Sains Malaysia (USM). Publisher Copyright: © 2017 Institute of Pharmacology, Polish Academy of Sciences Copyright: Copyright 2018 Elsevier B.V., All rights reserved.

PY - 2017/12

Y1 - 2017/12

N2 - Honey contains many active constituents and antioxidants such as polyphenols. Polyphenols are phytochemicals, a generic term for the several thousand plant-based molecules with antioxidant properties. Many in vitro studies in human cell cultures as well as many animal studies confirm the protective effect of polyphenols on a number of diseases such as cardiovascular diseases (CVD), diabetes, cancer, neurodegenerative diseases, pulmonary diseases, liver diseases and so on. Nevertheless, it is challenging to identify the specific biological mechanism underlying individual polyphenols and to determine how polyphenols impact human health. To date, several studies have attempted to elucidate the molecular pathway for specific polyphenols acting against particular diseases. In this review, we report on the various polyphenols present in different types of honey according to their classification, source, and specific functions and discuss several of the honey polyphenols with the most therapeutic potential to exert an effect on the various pathologies of some major diseases including CVD, diabetes, cancer, and neurodegenerative diseases.

AB - Honey contains many active constituents and antioxidants such as polyphenols. Polyphenols are phytochemicals, a generic term for the several thousand plant-based molecules with antioxidant properties. Many in vitro studies in human cell cultures as well as many animal studies confirm the protective effect of polyphenols on a number of diseases such as cardiovascular diseases (CVD), diabetes, cancer, neurodegenerative diseases, pulmonary diseases, liver diseases and so on. Nevertheless, it is challenging to identify the specific biological mechanism underlying individual polyphenols and to determine how polyphenols impact human health. To date, several studies have attempted to elucidate the molecular pathway for specific polyphenols acting against particular diseases. In this review, we report on the various polyphenols present in different types of honey according to their classification, source, and specific functions and discuss several of the honey polyphenols with the most therapeutic potential to exert an effect on the various pathologies of some major diseases including CVD, diabetes, cancer, and neurodegenerative diseases.

KW - Antioxidants

KW - Cancer

KW - CVD

KW - Diabetes

KW - Honey

KW - Neurodegenerative disease

KW - Polyphenols

UR - https://www.scopus.com/pages/publications/85033387054

U2 - 10.1016/j.pharep.2017.07.002

DO - 10.1016/j.pharep.2017.07.002

M3 - Review Article

C2 - 29128800

AN - SCOPUS:85033387054

SN - 1734-1140

VL - 69

SP - 1194

EP - 1205

JO - Pharmacological Reports

JF - Pharmacological Reports

IS - 6

ER -

Beneficial roles of honey polyphenols against some human degenerative diseases: A review

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Cite this