Behavioral assays to study oxygen and carbon dioxide sensing in Caenorhabditis elegans

Teresa Rojo Romanos, Leelee Ng, Roger Pocock

Research output: Contribution to journalArticleOtherpeer-review


Animals use behavioral strategies to seek optimal environments. Population behavioral assays provide a robust means to determine the effect of genetic perturbations on the ability of animals to sense and respond to changes in the environment. Here, we describe a C. elegans population behavioral assay used to measure locomotory responses to changes in environmental oxygen (O2) and carbon dioxide (CO2) concentrations. These behavioral assays are high-throughput and enable examination of genetic, neuronal and circuit function.
Original languageEnglish
Article numbere2679
Number of pages14
Issue number1
Publication statusPublished - 5 Jan 2018


  • c. elegans
  • behavior
  • oxygen
  • carbon dioxide
  • sensing

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