Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

Simone M. Schoenwaelder, Kate E. Jarman, Elizabeth E. Gardiner, My Hua, Jianlin Qiao, Michael J. White, Emma C. Josefsson, Imala Alwis, Akiko Ono, Abbey Willcox, Robert K. Andrews, Kylie D. Mason, Hatem H. Salem, David C. S. Huang, Benjamin T. Kile, Andrew W. Roberts, Shaun P. Jackson

Research output: Contribution to journalArticleResearchpeer-review

247 Citations (Scopus)


Overall, these studies demonstrate that Bcl-xL-inhibitory BH3 mimetics not only induce thrombocytopenia, but also a transient thrombocytopathy that can undermine the hemostatic function of platelets
Original languageEnglish
Pages (from-to)1663-1674
Number of pages12
Issue number6
Publication statusPublished - 2011

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