Bayley-III cognitive and language scales in preterm children

Megan M. Spencer-Smith, Alicia J. Spittle, Katherine J. Lee, Lex W. Doyle, Peter J. Anderson

Research output: Contribution to journalArticleResearchpeer-review

Abstract

BACKGROUND: This study aimed to assess the sensitivity and specificity of the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III), Cognitive and Language scales at 24 months for predicting cognitive impairments in preterm children at 4 years. METHODS: Children born <30 weeks' gestation completed the Bayley-III at 24 months and the Differential Ability Scale, Second Edition (DAS-II), at 4 years to assess cognitive functioning. Test norms and local term-born reference data were used to classify delay on the Bayley-III Cognitive and Language scales. Impairment on the DAS-II Global Conceptual Ability, Verbal, and Nonverbal Reasoning indices was classified relative to test norms. Scores < -1 SD relative to the mean were classified as mild/moderate delay or impairment, and scores < 22 SDs were classified as moderate delay or impairment. RESULTS: A total of 105 children completed the Bayley-III and DAS-II. The sensitivity of mild/ moderate cognitive delay on the Bayley-III for predicting impairment on DAS-II indices ranged from 29.4% to 38.5% and specificity ranged from 92.3% to 95.5%. The sensitivity of mild/moderate language delay on the Bayley-III for predicting impairment on DAS-II indices ranged from 40% to 46.7% and specificity ranged from 81.1% to 85.7%. The use of local reference data at 24 months to classify delay increased sensitivity but reduced specificity. Receiver operating curve analysis identified optimum cut-point scores for the Bayley-III that were more consistent with using local reference data than Bayley-III normative data. CONCLUSIONS: In our cohort of very preterm children, delay on the Bayley-III Cognitive and Language scales was not strongly predictive of future impairments. More children destined for later cognitive impairment were identified by using cut-points based on local reference data than Bayley-III norms.

Original languageEnglish
Pages (from-to)e1258-e1265
Number of pages10
JournalPediatrics
Volume135
Issue number5
DOIs
Publication statusPublished - 1 May 2015

Cite this

Spencer-Smith, Megan M. ; Spittle, Alicia J. ; Lee, Katherine J. ; Doyle, Lex W. ; Anderson, Peter J. / Bayley-III cognitive and language scales in preterm children. In: Pediatrics. 2015 ; Vol. 135, No. 5. pp. e1258-e1265.
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title = "Bayley-III cognitive and language scales in preterm children",
abstract = "BACKGROUND: This study aimed to assess the sensitivity and specificity of the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III), Cognitive and Language scales at 24 months for predicting cognitive impairments in preterm children at 4 years. METHODS: Children born <30 weeks' gestation completed the Bayley-III at 24 months and the Differential Ability Scale, Second Edition (DAS-II), at 4 years to assess cognitive functioning. Test norms and local term-born reference data were used to classify delay on the Bayley-III Cognitive and Language scales. Impairment on the DAS-II Global Conceptual Ability, Verbal, and Nonverbal Reasoning indices was classified relative to test norms. Scores < -1 SD relative to the mean were classified as mild/moderate delay or impairment, and scores < 22 SDs were classified as moderate delay or impairment. RESULTS: A total of 105 children completed the Bayley-III and DAS-II. The sensitivity of mild/ moderate cognitive delay on the Bayley-III for predicting impairment on DAS-II indices ranged from 29.4{\%} to 38.5{\%} and specificity ranged from 92.3{\%} to 95.5{\%}. The sensitivity of mild/moderate language delay on the Bayley-III for predicting impairment on DAS-II indices ranged from 40{\%} to 46.7{\%} and specificity ranged from 81.1{\%} to 85.7{\%}. The use of local reference data at 24 months to classify delay increased sensitivity but reduced specificity. Receiver operating curve analysis identified optimum cut-point scores for the Bayley-III that were more consistent with using local reference data than Bayley-III normative data. CONCLUSIONS: In our cohort of very preterm children, delay on the Bayley-III Cognitive and Language scales was not strongly predictive of future impairments. More children destined for later cognitive impairment were identified by using cut-points based on local reference data than Bayley-III norms.",
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Bayley-III cognitive and language scales in preterm children. / Spencer-Smith, Megan M.; Spittle, Alicia J.; Lee, Katherine J.; Doyle, Lex W.; Anderson, Peter J.

In: Pediatrics, Vol. 135, No. 5, 01.05.2015, p. e1258-e1265.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Bayley-III cognitive and language scales in preterm children

AU - Spencer-Smith, Megan M.

AU - Spittle, Alicia J.

AU - Lee, Katherine J.

AU - Doyle, Lex W.

AU - Anderson, Peter J.

PY - 2015/5/1

Y1 - 2015/5/1

N2 - BACKGROUND: This study aimed to assess the sensitivity and specificity of the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III), Cognitive and Language scales at 24 months for predicting cognitive impairments in preterm children at 4 years. METHODS: Children born <30 weeks' gestation completed the Bayley-III at 24 months and the Differential Ability Scale, Second Edition (DAS-II), at 4 years to assess cognitive functioning. Test norms and local term-born reference data were used to classify delay on the Bayley-III Cognitive and Language scales. Impairment on the DAS-II Global Conceptual Ability, Verbal, and Nonverbal Reasoning indices was classified relative to test norms. Scores < -1 SD relative to the mean were classified as mild/moderate delay or impairment, and scores < 22 SDs were classified as moderate delay or impairment. RESULTS: A total of 105 children completed the Bayley-III and DAS-II. The sensitivity of mild/ moderate cognitive delay on the Bayley-III for predicting impairment on DAS-II indices ranged from 29.4% to 38.5% and specificity ranged from 92.3% to 95.5%. The sensitivity of mild/moderate language delay on the Bayley-III for predicting impairment on DAS-II indices ranged from 40% to 46.7% and specificity ranged from 81.1% to 85.7%. The use of local reference data at 24 months to classify delay increased sensitivity but reduced specificity. Receiver operating curve analysis identified optimum cut-point scores for the Bayley-III that were more consistent with using local reference data than Bayley-III normative data. CONCLUSIONS: In our cohort of very preterm children, delay on the Bayley-III Cognitive and Language scales was not strongly predictive of future impairments. More children destined for later cognitive impairment were identified by using cut-points based on local reference data than Bayley-III norms.

AB - BACKGROUND: This study aimed to assess the sensitivity and specificity of the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III), Cognitive and Language scales at 24 months for predicting cognitive impairments in preterm children at 4 years. METHODS: Children born <30 weeks' gestation completed the Bayley-III at 24 months and the Differential Ability Scale, Second Edition (DAS-II), at 4 years to assess cognitive functioning. Test norms and local term-born reference data were used to classify delay on the Bayley-III Cognitive and Language scales. Impairment on the DAS-II Global Conceptual Ability, Verbal, and Nonverbal Reasoning indices was classified relative to test norms. Scores < -1 SD relative to the mean were classified as mild/moderate delay or impairment, and scores < 22 SDs were classified as moderate delay or impairment. RESULTS: A total of 105 children completed the Bayley-III and DAS-II. The sensitivity of mild/ moderate cognitive delay on the Bayley-III for predicting impairment on DAS-II indices ranged from 29.4% to 38.5% and specificity ranged from 92.3% to 95.5%. The sensitivity of mild/moderate language delay on the Bayley-III for predicting impairment on DAS-II indices ranged from 40% to 46.7% and specificity ranged from 81.1% to 85.7%. The use of local reference data at 24 months to classify delay increased sensitivity but reduced specificity. Receiver operating curve analysis identified optimum cut-point scores for the Bayley-III that were more consistent with using local reference data than Bayley-III normative data. CONCLUSIONS: In our cohort of very preterm children, delay on the Bayley-III Cognitive and Language scales was not strongly predictive of future impairments. More children destined for later cognitive impairment were identified by using cut-points based on local reference data than Bayley-III norms.

UR - http://www.scopus.com/inward/record.url?scp=84929493963&partnerID=8YFLogxK

U2 - 10.1542/peds.2014-3039

DO - 10.1542/peds.2014-3039

M3 - Article

VL - 135

SP - e1258-e1265

JO - Pediatrics

JF - Pediatrics

SN - 0031-4005

IS - 5

ER -