Basis of cargo recognition by importin αs: the power of structure

Gualtiero Alvisi, David A Jans

Research output: Contribution to journalShort SurveyResearchpeer-review

4 Citations (Scopus)


In this issue of Structure, Pumroy and colleagues have solved the crystal structure of the influenza virus polymerase PB2 C-terminal domain complexed with different Importin alphas. Combining molecular dynamics with structural and biochemical data, the so-far elusive basis for selectivity of binding to distinct different importin alphas is beginning to become accessible.
Original languageEnglish
Pages (from-to)251 - 252
Number of pages2
Issue number2
Publication statusPublished - 2015

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