TY - JOUR
T1 - Baseline characteristics of participants in the NAVKIDS2 trial
T2 - a patient navigator program in children with chronic kidney disease
AU - Guha, Chandana
AU - Khalid, Rabia
AU - van Zwieten, Anita
AU - Francis, Anna
AU - Hawley, Carmel M.
AU - Jauré, Allison
AU - Teixeira-Pinto, Armando
AU - Mallard, Alistair R.
AU - Bernier-Jean, Amelie
AU - Johnson, David W.
AU - Hahn, Deirdre
AU - Reidlinger, Donna
AU - Pascoe, Elaine M.
AU - Ryan, Elizabeth G.
AU - Mackie, Fiona
AU - McCarthy, Hugh J.
AU - Craig, Jonathan C.
AU - Varghese, Julie
AU - Kiriwandeniya, Charani
AU - Howard, Kirsten
AU - Larkins, Nicholas G.
AU - Macauley, Luke
AU - Walker, Amanda
AU - Howell, Martin
AU - Irving, Michelle
AU - Caldwell, Patrina H.Y.
AU - Woodleigh, Reginald
AU - Jesudason, Shilpanjali
AU - Carter, Simon A.
AU - Kennedy, Sean E.
AU - Alexander, Stephen I.
AU - McTaggart, Steven
AU - Wong, Germaine
N1 - Funding Information:
The study is funded by a National Health and Medical Research Council fund under the category: Medical Research Future Fund Targeted Call for Research: Rare Cancers, Rare Diseases and Unmet Need Initiative (APP1170021).
Publisher Copyright:
© 2022, The Author(s), under exclusive licence to International Pediatric Nephrology Association.
PY - 2023/5
Y1 - 2023/5
N2 - Background: Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to overcome barriers to accessing health services through care coordination. This trial aims to determine the effectiveness of a patient navigator program in children with CKD. Methods: The NAVKIDS2 trial is a multi-center, waitlisted, randomized controlled trial of patient navigators in children with CKD conducted at five sites across Australia. Children (0–16 years) with CKD from low socioeconomic status rural or remote areas were randomized to an intervention group or a waitlisted control group (to receive intervention after 6 months). The study primary and secondary endpoints include the self-rated health (SRH) (primary), and utility-based quality of life, progression of kidney dysfunction of the child, SRH, and satisfaction with healthcare of the caregiver at 6 months post-randomization. Results: The trial completed recruitment in October 2021 with expected completion of follow-up by October 2022. There were 162 patients enrolled with 80 and 82 patients randomized to the immediate intervention and waitlisted groups, respectively. Fifty-eight (36%) participants were from regional/remote areas, with a median (IQR) age of 9.5 (5.0, 13.0) years, 46% were of European Australian ethnicity, and 65% were male. A total of 109 children (67%) had CKD stages 1–5, 42 (26%) were transplant recipients, and 11 (7%) were receiving dialysis. Conclusion: The NAVKIDS2 trial is designed to evaluate the effectiveness of patient navigation in children with CKD from families experiencing socioeconomic disadvantage. Graphical abstract: [Figure not available: see fulltext.].
AB - Background: Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to overcome barriers to accessing health services through care coordination. This trial aims to determine the effectiveness of a patient navigator program in children with CKD. Methods: The NAVKIDS2 trial is a multi-center, waitlisted, randomized controlled trial of patient navigators in children with CKD conducted at five sites across Australia. Children (0–16 years) with CKD from low socioeconomic status rural or remote areas were randomized to an intervention group or a waitlisted control group (to receive intervention after 6 months). The study primary and secondary endpoints include the self-rated health (SRH) (primary), and utility-based quality of life, progression of kidney dysfunction of the child, SRH, and satisfaction with healthcare of the caregiver at 6 months post-randomization. Results: The trial completed recruitment in October 2021 with expected completion of follow-up by October 2022. There were 162 patients enrolled with 80 and 82 patients randomized to the immediate intervention and waitlisted groups, respectively. Fifty-eight (36%) participants were from regional/remote areas, with a median (IQR) age of 9.5 (5.0, 13.0) years, 46% were of European Australian ethnicity, and 65% were male. A total of 109 children (67%) had CKD stages 1–5, 42 (26%) were transplant recipients, and 11 (7%) were receiving dialysis. Conclusion: The NAVKIDS2 trial is designed to evaluate the effectiveness of patient navigation in children with CKD from families experiencing socioeconomic disadvantage. Graphical abstract: [Figure not available: see fulltext.].
KW - Adolescents
KW - Children
KW - Chronic kidney disease
KW - Patient navigator
KW - Social determinants of health
KW - Socioeconomic status
UR - http://www.scopus.com/inward/record.url?scp=85140322657&partnerID=8YFLogxK
U2 - 10.1007/s00467-022-05772-2
DO - 10.1007/s00467-022-05772-2
M3 - Article
C2 - 36264432
AN - SCOPUS:85140322657
SN - 0931-041X
VL - 38
SP - 1577
EP - 1590
JO - Pediatric Nephrology
JF - Pediatric Nephrology
IS - 5
ER -