Baseline characteristics of participants in the NAVKIDS2 trial: a patient navigator program in children with chronic kidney disease

Chandana Guha, Rabia Khalid, Anita van Zwieten, Anna Francis, Carmel M. Hawley, Allison Jauré, Armando Teixeira-Pinto, Alistair R. Mallard, Amelie Bernier-Jean, David W. Johnson, Deirdre Hahn, Donna Reidlinger, Elaine M. Pascoe, Elizabeth G. Ryan, Fiona Mackie, Hugh J. McCarthy, Jonathan C. Craig, Julie Varghese, Charani Kiriwandeniya, Kirsten HowardNicholas G. Larkins, Luke Macauley, Amanda Walker, Martin Howell, Michelle Irving, Patrina H.Y. Caldwell, Reginald Woodleigh, Shilpanjali Jesudason, Simon A. Carter, Sean E. Kennedy, Stephen I. Alexander, Steven McTaggart, Germaine Wong

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

Background: Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to overcome barriers to accessing health services through care coordination. This trial aims to determine the effectiveness of a patient navigator program in children with CKD. Methods: The NAVKIDS2 trial is a multi-center, waitlisted, randomized controlled trial of patient navigators in children with CKD conducted at five sites across Australia. Children (0–16 years) with CKD from low socioeconomic status rural or remote areas were randomized to an intervention group or a waitlisted control group (to receive intervention after 6 months). The study primary and secondary endpoints include the self-rated health (SRH) (primary), and utility-based quality of life, progression of kidney dysfunction of the child, SRH, and satisfaction with healthcare of the caregiver at 6 months post-randomization. Results: The trial completed recruitment in October 2021 with expected completion of follow-up by October 2022. There were 162 patients enrolled with 80 and 82 patients randomized to the immediate intervention and waitlisted groups, respectively. Fifty-eight (36%) participants were from regional/remote areas, with a median (IQR) age of 9.5 (5.0, 13.0) years, 46% were of European Australian ethnicity, and 65% were male. A total of 109 children (67%) had CKD stages 1–5, 42 (26%) were transplant recipients, and 11 (7%) were receiving dialysis. Conclusion: The NAVKIDS2 trial is designed to evaluate the effectiveness of patient navigation in children with CKD from families experiencing socioeconomic disadvantage. Graphical abstract: [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)1577-1590
Number of pages14
JournalPediatric Nephrology
Volume38
Issue number5
DOIs
Publication statusPublished - May 2023

Keywords

  • Adolescents
  • Children
  • Chronic kidney disease
  • Patient navigator
  • Social determinants of health
  • Socioeconomic status

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