Barrett's esophagus: Cancer and molecular biology

Michael K. Gibson; Arashinder S. Dhaliwal; Nicholas J Clemons; Wayne A. Phillips; Katerina Dvorak; Daniel Tong; Simon Law; E. Daniel Pirchi; Jari Räsänen; Mark J. Krasna; Kaushal Parikh; Kausilia K. Krishnadath; Yu Chen; Leonard Griffiths; Benjamin J. Colleypriest; J. Mark Farrant; David Tosh; Kiron M. Das; Manisha Bajpai

doi:10.1111/nyas.12252

Barrett's esophagus: Cancer and molecular biology

Michael K. Gibson, Arashinder S. Dhaliwal, Nicholas J Clemons, Wayne A. Phillips, Katerina Dvorak, Daniel Tong, Simon Law, E. Daniel Pirchi, Jari Räsänen, Mark J. Krasna, Kaushal Parikh, Kausilia K. Krishnadath, Yu Chen, Leonard Griffiths, Benjamin J. Colleypriest, J. Mark Farrant, David Tosh, Kiron M. Das, Manisha Bajpai

Research output: Contribution to journal › Article › Research › peer-review

26 Citations (Scopus)

Abstract

The following paper on the molecular biology of Barrett's esophagus (BE) includes commentaries on signaling pathways central to the development of BE including Hh, NF-κB, and IL-6/STAT3; surgical approaches for esophagectomy and classification of lesions by appropriate therapy; the debate over the merits of minimally invasive esophagectomy versus open surgery; outcomes for patients with pharyngolaryngoesophagectomy; the applications of neoadjuvant chemotherapy and chemoradiotherapy; animal models examining the surgical models of BE and esophageal adenocarcinoma; the roles of various morphogens and Cdx2 in BE; and the use of in vitro BE models for chemoprevention studies.

Original language	English
Pages (from-to)	296-314
Number of pages	19
Journal	Annals of the New York Academy of Sciences
Volume	1300
Issue number	1
DOIs	https://doi.org/10.1111/nyas.12252
Publication status	Published - Oct 2013
Externally published	Yes

Keywords

Barrett's esophagus
Esophageal adenocarcinoma
Esophagectomy
MIE

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/nyas.12252

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Gibson, M. K., Dhaliwal, A. S., Clemons, N. J., Phillips, W. A., Dvorak, K., Tong, D., Law, S., Pirchi, E. D., Räsänen, J., Krasna, M. J., Parikh, K., Krishnadath, K. K., Chen, Y., Griffiths, L., Colleypriest, B. J., Farrant, J. M., Tosh, D., Das, K. M., & Bajpai, M. (2013). Barrett's esophagus: Cancer and molecular biology. Annals of the New York Academy of Sciences, 1300(1), 296-314. https://doi.org/10.1111/nyas.12252

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title = "Barrett's esophagus: Cancer and molecular biology",

abstract = "The following paper on the molecular biology of Barrett's esophagus (BE) includes commentaries on signaling pathways central to the development of BE including Hh, NF-κB, and IL-6/STAT3; surgical approaches for esophagectomy and classification of lesions by appropriate therapy; the debate over the merits of minimally invasive esophagectomy versus open surgery; outcomes for patients with pharyngolaryngoesophagectomy; the applications of neoadjuvant chemotherapy and chemoradiotherapy; animal models examining the surgical models of BE and esophageal adenocarcinoma; the roles of various morphogens and Cdx2 in BE; and the use of in vitro BE models for chemoprevention studies.",

keywords = "Barrett's esophagus, Esophageal adenocarcinoma, Esophagectomy, MIE",

author = "Gibson, {Michael K.} and Dhaliwal, {Arashinder S.} and Clemons, {Nicholas J} and Phillips, {Wayne A.} and Katerina Dvorak and Daniel Tong and Simon Law and Pirchi, {E. Daniel} and Jari R{\"a}s{\"a}nen and Krasna, {Mark J.} and Kaushal Parikh and Krishnadath, {Kausilia K.} and Yu Chen and Leonard Griffiths and Colleypriest, {Benjamin J.} and Farrant, {J. Mark} and David Tosh and Das, {Kiron M.} and Manisha Bajpai",

year = "2013",

month = oct,

doi = "10.1111/nyas.12252",

language = "English",

volume = "1300",

pages = "296--314",

journal = "Annals of the New York Academy of Sciences",

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Gibson, MK, Dhaliwal, AS, Clemons, NJ, Phillips, WA, Dvorak, K, Tong, D, Law, S, Pirchi, ED, Räsänen, J, Krasna, MJ, Parikh, K, Krishnadath, KK, Chen, Y, Griffiths, L, Colleypriest, BJ, Farrant, JM, Tosh, D, Das, KM & Bajpai, M 2013, 'Barrett's esophagus: Cancer and molecular biology', Annals of the New York Academy of Sciences, vol. 1300, no. 1, pp. 296-314. https://doi.org/10.1111/nyas.12252

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T2 - Cancer and molecular biology

AU - Gibson, Michael K.

AU - Dhaliwal, Arashinder S.

AU - Clemons, Nicholas J

AU - Phillips, Wayne A.

AU - Dvorak, Katerina

AU - Tong, Daniel

AU - Law, Simon

AU - Pirchi, E. Daniel

AU - Räsänen, Jari

AU - Krasna, Mark J.

AU - Parikh, Kaushal

AU - Krishnadath, Kausilia K.

AU - Chen, Yu

AU - Griffiths, Leonard

AU - Colleypriest, Benjamin J.

AU - Farrant, J. Mark

AU - Tosh, David

AU - Das, Kiron M.

AU - Bajpai, Manisha

PY - 2013/10

Y1 - 2013/10

N2 - The following paper on the molecular biology of Barrett's esophagus (BE) includes commentaries on signaling pathways central to the development of BE including Hh, NF-κB, and IL-6/STAT3; surgical approaches for esophagectomy and classification of lesions by appropriate therapy; the debate over the merits of minimally invasive esophagectomy versus open surgery; outcomes for patients with pharyngolaryngoesophagectomy; the applications of neoadjuvant chemotherapy and chemoradiotherapy; animal models examining the surgical models of BE and esophageal adenocarcinoma; the roles of various morphogens and Cdx2 in BE; and the use of in vitro BE models for chemoprevention studies.

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KW - Barrett's esophagus

KW - Esophageal adenocarcinoma

KW - Esophagectomy

KW - MIE

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SN - 0077-8923

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JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

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Barrett's esophagus: Cancer and molecular biology

Abstract

Keywords

UN SDGs

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