Projects per year
Abstract
Few treatment options are available for oseltamivir-resistant influenza. It has been proposed that baloxavir can be effective in this setting due to its distinct mechanism of action but clinical experience is lacking for immunocompromised patients. We report two such cases treated with baloxavir after failure of oseltamivir and detection of oseltamivir resistance mutations. Baloxavir/zanamivir combination therapy was effective in one patient, but persistent viral shedding was noted with baloxavir monotherapy in the other patient.
Original language | English |
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Article number | e13542 |
Number of pages | 5 |
Journal | Transplant Infectious Disease |
Volume | 23 |
Issue number | 3 |
DOIs | |
Publication status | Published - Jun 2021 |
Keywords
- CAR-T cell therapy
- H275Y
- lung transplant
- lymphoma
- neuraminidase inhibitor
Projects
- 2 Finished
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Integrating genomic and artificial intelligence approaches to combat antimicrobial resistance
Macesic, N. (Primary Chief Investigator (PCI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/20 → 31/12/24
Project: Research
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Genomic approaches for understanding resistance to polymyxins in carbapenem-resistant Enterobacteriaceae
Macesic, N. (Primary Chief Investigator (PCI)) & Peleg, A. (Supervisor)
1/08/19 → 31/03/21
Project: Research