Balamuthia mandrillaris brain abscess successfully treated with complete surgical excision and prolonged combination antimicrobial therapy

Case report

Joseph S. Doyle, Emer Campbell, Andrew Fuller, Denis W. Spelman, Rhoda Cameron, Grregory Malham, Douglas Gin, Sharon R. Lewin

Research output: Contribution to journalArticleOtherpeer-review

18 Citations (Scopus)

Abstract

Amoebic encephalitis is an uncommon and usually fatal condition. This case describes successful treatment of a Balamuthia mandrillaris brain abscess using prolonged antimicrobial agents with complete excision. It illustrates the risk of dissemination from cutaneous to cerebral amoebic lesions, potential progression with corticosteroid therapy, and the prospect for curative excision.
Original languageEnglish
Pages (from-to)458-462
Number of pages5
JournalJournal of Neurosurgery
Volume114
Issue number2
DOIs
Publication statusPublished - 2011

Keywords

  • Balamuthia mandrillaris
  • brain abscess
  • free-living amoeba

Cite this

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Balamuthia mandrillaris brain abscess successfully treated with complete surgical excision and prolonged combination antimicrobial therapy : Case report. / Doyle, Joseph S.; Campbell, Emer; Fuller, Andrew ; Spelman, Denis W.; Cameron, Rhoda; Malham, Grregory ; Gin, Douglas; Lewin, Sharon R.

In: Journal of Neurosurgery, Vol. 114, No. 2, 2011, p. 458-462.

Research output: Contribution to journalArticleOtherpeer-review

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AU - Gin, Douglas

AU - Lewin, Sharon R.

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AB - Amoebic encephalitis is an uncommon and usually fatal condition. This case describes successful treatment of a Balamuthia mandrillaris brain abscess using prolonged antimicrobial agents with complete excision. It illustrates the risk of dissemination from cutaneous to cerebral amoebic lesions, potential progression with corticosteroid therapy, and the prospect for curative excision.

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