Balamuthia mandrillaris brain abscess successfully treated with complete surgical excision and prolonged combination antimicrobial therapy: Case report

Joseph S. Doyle; Emer Campbell; Andrew  Fuller; Denis W. Spelman; Rhoda Cameron; Gregory  Malham; Douglas Gin; Sharon R. Lewin

doi:10.3171/2010.10.JNS10677

Balamuthia mandrillaris brain abscess successfully treated with complete surgical excision and prolonged combination antimicrobial therapy: Case report

Joseph S. Doyle, Emer Campbell, Andrew Fuller, Denis W. Spelman, Rhoda Cameron, Gregory Malham, Douglas Gin, Sharon R. Lewin

Infectious Diseases

Research output: Contribution to journal › Article › Other › peer-review

40 Citations (Scopus)

Abstract

Amoebic encephalitis is an uncommon and usually fatal condition. This case describes successful treatment of a Balamuthia mandrillaris brain abscess using prolonged antimicrobial agents with complete excision. It illustrates the risk of dissemination from cutaneous to cerebral amoebic lesions, potential progression with corticosteroid therapy, and the prospect for curative excision.

Original language	English
Pages (from-to)	458-462
Number of pages	5
Journal	Journal of Neurosurgery
Volume	114
Issue number	2
DOIs	https://doi.org/10.3171/2010.10.JNS10677
Publication status	Published - 2011

Keywords

Balamuthia mandrillaris
brain abscess
free-living amoeba

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10.3171/2010.10.JNS10677

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abstract = "Amoebic encephalitis is an uncommon and usually fatal condition. This case describes successful treatment of a Balamuthia mandrillaris brain abscess using prolonged antimicrobial agents with complete excision. It illustrates the risk of dissemination from cutaneous to cerebral amoebic lesions, potential progression with corticosteroid therapy, and the prospect for curative excision.",

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AU - Spelman, Denis W.

AU - Cameron, Rhoda

AU - Malham, Gregory

AU - Gin, Douglas

AU - Lewin, Sharon R.

PY - 2011

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AB - Amoebic encephalitis is an uncommon and usually fatal condition. This case describes successful treatment of a Balamuthia mandrillaris brain abscess using prolonged antimicrobial agents with complete excision. It illustrates the risk of dissemination from cutaneous to cerebral amoebic lesions, potential progression with corticosteroid therapy, and the prospect for curative excision.

KW - Balamuthia mandrillaris

KW - brain abscess

KW - free-living amoeba

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M3 - Article

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AN - SCOPUS:79551713882

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ER -

Balamuthia mandrillaris brain abscess successfully treated with complete surgical excision and prolonged combination antimicrobial therapy: Case report

Abstract

Keywords

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