Bacteriocin (mutacin) production by Streptococcus mutans genome sequence reference strain UA159: Elucidation of the antimicrobial repertoire by genetic dissection

J. D F Hale, Yi Tian Ting, Ralph W. Jack, John R. Tagg, N. C K Heng

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Abstract

Streptococcus mutans UA159, the genome sequence reference strain, exhibits nonlantibiotic mutacin activity. In this study, bioinformatic and mutational analyses were employed to demonstrate that the antimicrobial repertoire of strain UA159 includes mutacin IV (specified by the nlm locus) and a newly identified bacteriocin, mutacin V (encoded by SMU.1914c).

Original languageEnglish
Pages (from-to)7613-7617
Number of pages5
JournalApplied and Environmental Microbiology
Volume71
Issue number11
DOIs
Publication statusPublished - Nov 2005
Externally publishedYes

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