Toxin-antitoxin systems control the viability of bacteria. Toxins of the zeta family poison cell wall synthesis and thereby ultimately cause lysis of the cell. Here we describe the mechanism of epsilon-zeta toxin-anti - toxin systems, how they might attenuate infections and how humans could utilize them as lead compounds for the development of antibiotics.
|Translated title of the contribution||Bacterial programmed cell death: The lethal mechanism of the zeta toxins|
|Number of pages||3|
|Publication status||Published - Mar 2013|