Bacterial Artificial Chromosomes

Kumaran Narayanan (Editor)

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    Abstract

    Bacterial Artificial Chromosomes, Second Edition expands upon the previous edition with current, detailed methods developed for working with BACs. Updated chapters included in this edition present fundamental techniques used for BAC construction and characterization, advanced procedures for introducing modifications, achieving gene expression from BAC vectors, applications of BACs in model organisms, and medical genetics and drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step reproducible laboratory protocols, and tips to troubleshoot and avoid known pitfalls. Authoritative and cutting-edge, Bacterial Artificial Chromosomes, Second Edition seeks to aid scientists in advancing their research using these exciting BAC techniques and strategies.

    Original languageEnglish
    Place of PublicationNew York, USA
    PublisherSpringer
    Number of pages343
    Edition2nd
    ISBN (Electronic)9781493916528
    ISBN (Print)9781493916511
    DOIs
    Publication statusPublished - 2015

    Publication series

    NameMethods in Molecular Biology
    PublisherSpringer
    Volume1227
    ISSN (Print)1064-3745
    ISSN (Electronic)1940-6029

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