B Cells Hit a Class Ceiling in the Germinal Center

Lucy Cooper; Kim L. Good-Jacobson

doi:10.1016/j.immuni.2019.07.004

B Cells Hit a Class Ceiling in the Germinal Center

Research output: Contribution to journal › Short Survey › Other › peer-review

Abstract

Class-switch recombination (CSR) provides diverse effector functions to B cells. In this issue of Immunity, Roco et al. (2019) refute long-standing dogma that germinal centers are the principal location for CSR; instead, CSR predominantly occurs early post immunization and declines during germinal center formation.

Original language	English
Pages (from-to)	206-208
Number of pages	3
Journal	Immunity
Volume	51
Issue number	2
DOIs	https://doi.org/10.1016/j.immuni.2019.07.004
Publication status	Published - 20 Aug 2019

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10.1016/j.immuni.2019.07.004

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title = "B Cells Hit a Class Ceiling in the Germinal Center",

abstract = "Class-switch recombination (CSR) provides diverse effector functions to B cells. In this issue of Immunity, Roco et al. (2019) refute long-standing dogma that germinal centers are the principal location for CSR; instead, CSR predominantly occurs early post immunization and declines during germinal center formation.",

author = "Lucy Cooper and Good-Jacobson, {Kim L.}",

year = "2019",

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day = "20",

doi = "10.1016/j.immuni.2019.07.004",

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T1 - B Cells Hit a Class Ceiling in the Germinal Center

AU - Cooper, Lucy

AU - Good-Jacobson, Kim L.

PY - 2019/8/20

Y1 - 2019/8/20

N2 - Class-switch recombination (CSR) provides diverse effector functions to B cells. In this issue of Immunity, Roco et al. (2019) refute long-standing dogma that germinal centers are the principal location for CSR; instead, CSR predominantly occurs early post immunization and declines during germinal center formation.

AB - Class-switch recombination (CSR) provides diverse effector functions to B cells. In this issue of Immunity, Roco et al. (2019) refute long-standing dogma that germinal centers are the principal location for CSR; instead, CSR predominantly occurs early post immunization and declines during germinal center formation.

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U2 - 10.1016/j.immuni.2019.07.004

DO - 10.1016/j.immuni.2019.07.004

M3 - Short Survey

AN - SCOPUS:85070658785

SN - 1074-7613

VL - 51

SP - 206

EP - 208

JO - Immunity

JF - Immunity

IS - 2

ER -

B Cells Hit a Class Ceiling in the Germinal Center

Abstract

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