B Cell Receptor Transgenic Mice as Tools to Study Memory B Cells

Isaak Quast

doi:10.1007/978-1-0716-3950-4_10

B Cell Receptor Transgenic Mice as Tools to Study Memory B Cells

Isaak Quast

Immunology Alfred Hospital

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

1 Citation (Scopus)

Abstract

B cell receptor (BCR) transgenic mice allow the control of the initial target (antigen) specificity of naïve B cells and to investigate their properties following activation. Here, I describe how BCR transgenic B cells can be used in combination with adoptive cell transfer and immunization models to study memory B cell formation and reactivation.

Original language	English
Title of host publication	Memory B-Cells
Subtitle of host publication	Methods and Protocols
Editors	Kim L. Good-Jacobson
Place of Publication	New York NY USA
Publisher	Humana Press
Chapter	10
Pages	131-139
Number of pages	9
Edition	1st
ISBN (Electronic)	9781071639504
ISBN (Print)	9781071639498, 9781071639528
DOIs	https://doi.org/10.1007/978-1-0716-3950-4_10
Publication status	Published - 2024

Publication series

Name	Methods in Molecular Biology
Volume	2826
ISSN (Print)	1064-3745
ISSN (Electronic)	1940-6029

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adoptive cell transfer
B cell receptor transgenic mice
Germinal center
Memory B cells
Vaccine immune responses

Access to Document

10.1007/978-1-0716-3950-4_10

Cite this

@inbook{d439fe13b3b3442e96b20111e1f07d03,

title = "B Cell Receptor Transgenic Mice as Tools to Study Memory B Cells",

abstract = "B cell receptor (BCR) transgenic mice allow the control of the initial target (antigen) specificity of na{\"i}ve B cells and to investigate their properties following activation. Here, I describe how BCR transgenic B cells can be used in combination with adoptive cell transfer and immunization models to study memory B cell formation and reactivation.",

keywords = "Adoptive cell transfer, B cell receptor transgenic mice, Germinal center, Memory B cells, Vaccine immune responses",

author = "Isaak Quast",

note = "Publisher Copyright: {\textcopyright} 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2024",

doi = "10.1007/978-1-0716-3950-4\_10",

language = "English",

isbn = "9781071639498",

series = "Methods in Molecular Biology",

publisher = "Humana Press",

pages = "131--139",

editor = "Good-Jacobson, \{Kim L.\}",

booktitle = "Memory B-Cells",

address = "United States of America",

edition = "1st",

}

TY - CHAP

T1 - B Cell Receptor Transgenic Mice as Tools to Study Memory B Cells

AU - Quast, Isaak

PY - 2024

Y1 - 2024

N2 - B cell receptor (BCR) transgenic mice allow the control of the initial target (antigen) specificity of naïve B cells and to investigate their properties following activation. Here, I describe how BCR transgenic B cells can be used in combination with adoptive cell transfer and immunization models to study memory B cell formation and reactivation.

AB - B cell receptor (BCR) transgenic mice allow the control of the initial target (antigen) specificity of naïve B cells and to investigate their properties following activation. Here, I describe how BCR transgenic B cells can be used in combination with adoptive cell transfer and immunization models to study memory B cell formation and reactivation.

KW - Adoptive cell transfer

KW - B cell receptor transgenic mice

KW - Germinal center

KW - Memory B cells

KW - Vaccine immune responses

UR - https://www.scopus.com/pages/publications/85199015086

U2 - 10.1007/978-1-0716-3950-4_10

DO - 10.1007/978-1-0716-3950-4_10

M3 - Chapter (Book)

C2 - 39017890

AN - SCOPUS:85199015086

SN - 9781071639498

SN - 9781071639528

T3 - Methods in Molecular Biology

SP - 131

EP - 139

BT - Memory B-Cells

A2 - Good-Jacobson, Kim L.

PB - Humana Press

CY - New York NY USA

ER -

B Cell Receptor Transgenic Mice as Tools to Study Memory B Cells

Abstract

Publication series

UN SDGs

Keywords

Access to Document

Other files and links

Cite this