B-cell differentiation: Instructive one day, stochastic the next

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Abstract

Three recent papers provide striking insight into the mechanisms used to regulate B-cell differentiation. They demonstrate that B-cell fate choice can be stochastic, directed, inherited, or some combination of these, depending on the circumstances. The trick is going to be working out which is important when.

Original languageEnglish
Pages (from-to)R235-R237
Number of pages3
JournalCurrent Biology
Volume22
Issue number7
DOIs
Publication statusPublished - 10 Apr 2012
Externally publishedYes

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