Aziridination of alkenes with N-substituted hydrazines mediated by iodobenzene diacetate

Jiayin Li, Jiang Lin Liang, Philip Wai Hong Chan, Chi Ming Che

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Abstract

Aziridination of a variety of alkenes with N-substituted hydrazines mediated by iodobenzene diacetate under mild conditions (K2CO 3, CH2Cl2) and ambient temperature were achieved in good to excellent yields (up to 99%), and conversions. The practicality and simplicity of this C-N bond formation protocol was exemplified by its application to the aziridination of cholesteryl acetate in a stereoselective manner.

Original languageEnglish
Pages (from-to)2685-2688
Number of pages4
JournalTetrahedron Letters
Volume45
Issue number12
DOIs
Publication statusPublished - 15 Mar 2004
Externally publishedYes

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