Autophagy in disease

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

16 Citations (Scopus)

Abstract

Autophagy is a cellular quality control process by which cytoplasmic constituents including proteins, protein aggregates, organelles, and invading pathogens can be delivered to lysosomes for degradation. Autophagy is activated in response to changes in the internal status of the cell and/or changes in the extracellular environment. It is therefore essential for the maintenance of cellular homeostasis and for an efficient response to cellular stresses. As such autophagy has been implicated either in the pathogenesis, or response to a wide variety of diseases, bacterial, and viral infections, and ageing.
Original languageEnglish
Title of host publicationProtein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols
EditorsPeter Bross, Niels Gregersen
Place of PublicationUK
PublisherHumana Press
Pages79 - 92
Number of pages14
Edition1st
ISBN (Print)9781607617556
DOIs
Publication statusPublished - 2010

Cite this

Mijaljica, D., Prescott, M., & Devenish, R. J. (2010). Autophagy in disease. In P. Bross, & N. Gregersen (Eds.), Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols (1st ed., pp. 79 - 92). UK: Humana Press. https://doi.org/10.1007/978-1-60761-756-3_5
Mijaljica, Dalibor ; Prescott, Mark ; Devenish, Rodney James. / Autophagy in disease. Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols. editor / Peter Bross ; Niels Gregersen. 1st. ed. UK : Humana Press, 2010. pp. 79 - 92
@inbook{26b56647b5174378b349cb8279502450,
title = "Autophagy in disease",
abstract = "Autophagy is a cellular quality control process by which cytoplasmic constituents including proteins, protein aggregates, organelles, and invading pathogens can be delivered to lysosomes for degradation. Autophagy is activated in response to changes in the internal status of the cell and/or changes in the extracellular environment. It is therefore essential for the maintenance of cellular homeostasis and for an efficient response to cellular stresses. As such autophagy has been implicated either in the pathogenesis, or response to a wide variety of diseases, bacterial, and viral infections, and ageing.",
author = "Dalibor Mijaljica and Mark Prescott and Devenish, {Rodney James}",
year = "2010",
doi = "10.1007/978-1-60761-756-3_5",
language = "English",
isbn = "9781607617556",
pages = "79 -- 92",
editor = "Peter Bross and Niels Gregersen",
booktitle = "Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols",
publisher = "Humana Press",
address = "United States of America",
edition = "1st",

}

Mijaljica, D, Prescott, M & Devenish, RJ 2010, Autophagy in disease. in P Bross & N Gregersen (eds), Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols. 1st edn, Humana Press, UK, pp. 79 - 92. https://doi.org/10.1007/978-1-60761-756-3_5

Autophagy in disease. / Mijaljica, Dalibor; Prescott, Mark; Devenish, Rodney James.

Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols. ed. / Peter Bross; Niels Gregersen. 1st. ed. UK : Humana Press, 2010. p. 79 - 92.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

TY - CHAP

T1 - Autophagy in disease

AU - Mijaljica, Dalibor

AU - Prescott, Mark

AU - Devenish, Rodney James

PY - 2010

Y1 - 2010

N2 - Autophagy is a cellular quality control process by which cytoplasmic constituents including proteins, protein aggregates, organelles, and invading pathogens can be delivered to lysosomes for degradation. Autophagy is activated in response to changes in the internal status of the cell and/or changes in the extracellular environment. It is therefore essential for the maintenance of cellular homeostasis and for an efficient response to cellular stresses. As such autophagy has been implicated either in the pathogenesis, or response to a wide variety of diseases, bacterial, and viral infections, and ageing.

AB - Autophagy is a cellular quality control process by which cytoplasmic constituents including proteins, protein aggregates, organelles, and invading pathogens can be delivered to lysosomes for degradation. Autophagy is activated in response to changes in the internal status of the cell and/or changes in the extracellular environment. It is therefore essential for the maintenance of cellular homeostasis and for an efficient response to cellular stresses. As such autophagy has been implicated either in the pathogenesis, or response to a wide variety of diseases, bacterial, and viral infections, and ageing.

UR - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20700706

U2 - 10.1007/978-1-60761-756-3_5

DO - 10.1007/978-1-60761-756-3_5

M3 - Chapter (Book)

SN - 9781607617556

SP - 79

EP - 92

BT - Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols

A2 - Bross, Peter

A2 - Gregersen, Niels

PB - Humana Press

CY - UK

ER -

Mijaljica D, Prescott M, Devenish RJ. Autophagy in disease. In Bross P, Gregersen N, editors, Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols. 1st ed. UK: Humana Press. 2010. p. 79 - 92 https://doi.org/10.1007/978-1-60761-756-3_5