Automated Determination of Nickel and Copper by Liquid Chromatography with Electrochemical and Spectrophotometric Detection

A microprocessor-based instrumental method for automated monitoring of nickel and copper in a wide variety of matrices found in industrial plant situations has been developed. in situ formation of dlthiocarbamate complexes, separation of complexes by high-performance reversed-phase liquid chromatography, and dual electrochemical and UV/visible spectrophotometric detection are included as integral components of the monitoring system. The unusual versatility associated with the separation and detection system provides the analyst with methodology to determine nickel and copper down to trace levels and with extremely large variation in concentration ratio. Data obtained during the trial period of operation suggest that matrix and other interferences are likely to be minimal after appropriate choice of operating parameters.