Autoimmune disease leading to pulmonary AL amyloidosis and pulmonary hypertension

Claire M. Ellender, Catriona McLean, Trevor J. Williams, Gregory I. Snell, Helen M. Whitford

Research output: Contribution to journalArticleOtherpeer-review

4 Citations (Scopus)


A 33-year-old woman with past history of Sjögren's syndrome and systemic lupus erythematosus presented with dyspnea and syncope secondary to pulmonary hypertension. After progressive symptoms over 4 years, she received bilateral lung transplantation.Histopathology of the explanted lungs showed isolated pulmonary amyloid light-chain amyloidosis and pulmonary cysts. No evidence of systemic amyloidosis was found at the time of transplantation. Seven years post lung transplantation, she remains well with no evidence of systemic amyloidosis recurrence.

Original languageEnglish
Pages (from-to)78-81
Number of pages4
JournalRespirology Case Reports
Issue number2
Publication statusPublished - 2015


  • Amyloidosis
  • Pulmonary hypertension
  • Sjögren's syndrome

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