Autism

One or many spectrums?

Alexandra Ure, Veronica Rose, Charmaine Bernie, Katrina Williams

Research output: Contribution to journalArticleOtherpeer-review

1 Citation (Scopus)

Abstract

Our conceptualisation of autism spectrum disorder has changed over time, with recent classifications reflecting a heterogeneous clinical presentation now regularly encountered in routine general paediatric practice. As the prevalence of autism and associated demands for services have increased so has research into understanding the cause and trials aimed at providing best care and intervention. However, the heterogeneity of autism has meant that no single aetiology can account for all differences in presentation, and not all children benefit from broad-based interventions. Now is the time to rethink how best to understand individual differences in order to focus research efforts and take steps towards more sophisticated strategies that go beyond the behaviours we look for when making an autism diagnosis. We suggest adopting a dimensional approach to autism assessment, with the consideration of eight spectrums of abilities, ways of thinking and behaviour. This eight-spectrum approach will assist clinicians to consider each individual's strengths and needs and personalise interventions and support accordingly. Profiling individual skills across these dimensions may also provide researchers with a greater capacity to link causal pathways with specific phenotypes, which is needed to develop precision medicine for autism.

Original languageEnglish
Pages (from-to)1068-1072
Number of pages5
JournalJournal of Paediatrics and Child Health
Volume54
Issue number10
DOIs
Publication statusPublished - 1 Oct 2018
Externally publishedYes

Cite this

Ure, Alexandra ; Rose, Veronica ; Bernie, Charmaine ; Williams, Katrina. / Autism : One or many spectrums?. In: Journal of Paediatrics and Child Health. 2018 ; Vol. 54, No. 10. pp. 1068-1072.
@article{5d3161df1a034bb7b2f510962f3ea19b,
title = "Autism: One or many spectrums?",
abstract = "Our conceptualisation of autism spectrum disorder has changed over time, with recent classifications reflecting a heterogeneous clinical presentation now regularly encountered in routine general paediatric practice. As the prevalence of autism and associated demands for services have increased so has research into understanding the cause and trials aimed at providing best care and intervention. However, the heterogeneity of autism has meant that no single aetiology can account for all differences in presentation, and not all children benefit from broad-based interventions. Now is the time to rethink how best to understand individual differences in order to focus research efforts and take steps towards more sophisticated strategies that go beyond the behaviours we look for when making an autism diagnosis. We suggest adopting a dimensional approach to autism assessment, with the consideration of eight spectrums of abilities, ways of thinking and behaviour. This eight-spectrum approach will assist clinicians to consider each individual's strengths and needs and personalise interventions and support accordingly. Profiling individual skills across these dimensions may also provide researchers with a greater capacity to link causal pathways with specific phenotypes, which is needed to develop precision medicine for autism.",
author = "Alexandra Ure and Veronica Rose and Charmaine Bernie and Katrina Williams",
year = "2018",
month = "10",
day = "1",
doi = "10.1111/jpc.14176",
language = "English",
volume = "54",
pages = "1068--1072",
journal = "Journal of Paediatrics and Child Health",
issn = "1034-4810",
publisher = "Wiley-Blackwell",
number = "10",

}

Autism : One or many spectrums? / Ure, Alexandra; Rose, Veronica; Bernie, Charmaine; Williams, Katrina.

In: Journal of Paediatrics and Child Health, Vol. 54, No. 10, 01.10.2018, p. 1068-1072.

Research output: Contribution to journalArticleOtherpeer-review

TY - JOUR

T1 - Autism

T2 - One or many spectrums?

AU - Ure, Alexandra

AU - Rose, Veronica

AU - Bernie, Charmaine

AU - Williams, Katrina

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Our conceptualisation of autism spectrum disorder has changed over time, with recent classifications reflecting a heterogeneous clinical presentation now regularly encountered in routine general paediatric practice. As the prevalence of autism and associated demands for services have increased so has research into understanding the cause and trials aimed at providing best care and intervention. However, the heterogeneity of autism has meant that no single aetiology can account for all differences in presentation, and not all children benefit from broad-based interventions. Now is the time to rethink how best to understand individual differences in order to focus research efforts and take steps towards more sophisticated strategies that go beyond the behaviours we look for when making an autism diagnosis. We suggest adopting a dimensional approach to autism assessment, with the consideration of eight spectrums of abilities, ways of thinking and behaviour. This eight-spectrum approach will assist clinicians to consider each individual's strengths and needs and personalise interventions and support accordingly. Profiling individual skills across these dimensions may also provide researchers with a greater capacity to link causal pathways with specific phenotypes, which is needed to develop precision medicine for autism.

AB - Our conceptualisation of autism spectrum disorder has changed over time, with recent classifications reflecting a heterogeneous clinical presentation now regularly encountered in routine general paediatric practice. As the prevalence of autism and associated demands for services have increased so has research into understanding the cause and trials aimed at providing best care and intervention. However, the heterogeneity of autism has meant that no single aetiology can account for all differences in presentation, and not all children benefit from broad-based interventions. Now is the time to rethink how best to understand individual differences in order to focus research efforts and take steps towards more sophisticated strategies that go beyond the behaviours we look for when making an autism diagnosis. We suggest adopting a dimensional approach to autism assessment, with the consideration of eight spectrums of abilities, ways of thinking and behaviour. This eight-spectrum approach will assist clinicians to consider each individual's strengths and needs and personalise interventions and support accordingly. Profiling individual skills across these dimensions may also provide researchers with a greater capacity to link causal pathways with specific phenotypes, which is needed to develop precision medicine for autism.

UR - http://www.scopus.com/inward/record.url?scp=85054398791&partnerID=8YFLogxK

U2 - 10.1111/jpc.14176

DO - 10.1111/jpc.14176

M3 - Article

VL - 54

SP - 1068

EP - 1072

JO - Journal of Paediatrics and Child Health

JF - Journal of Paediatrics and Child Health

SN - 1034-4810

IS - 10

ER -