Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions (Scientific Reports, (2020), 10, 1, (1495), 10.1038/s41598-020-58362-3)

Marie Laëtitia Thézénas; Bianca De Leo; Alexis Laux-Biehlmann; Cemsel Bafligil; Bernd Elger; Thomas Tapmeier; Karl Morten; Nilufer Rahmioglu; Stephanie G. Dakin; Philip Charles; Fernando Estrada Martinez; Graham Steers; Oliver M. Fischer; Joerg Mueller; Holger Hess-Stumpp; Andreas Steinmeyer; Sanjiv Manek; Krina T. Zondervan; Stephen H Kennedy; Christian M. Becker; Catherine Shang; Thomas M. Zollner; Benedikt M. Kessler; Udo Oppermann

doi:10.1038/s41598-020-62492-z

Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions (Scientific Reports, (2020), 10, 1, (1495), 10.1038/s41598-020-58362-3)

Marie Laëtitia Thézénas, Bianca De Leo, Alexis Laux-Biehlmann, Cemsel Bafligil, Bernd Elger, Thomas Tapmeier, Karl Morten, Nilufer Rahmioglu, Stephanie G. Dakin, Philip Charles, Fernando Estrada Martinez, Graham Steers, Oliver M. Fischer, Joerg Mueller, Holger Hess-Stumpp, Andreas Steinmeyer, Sanjiv Manek, Krina T. Zondervan, Stephen H Kennedy, Christian M. BeckerCatherine Shang, Thomas M. Zollner, Benedikt M. Kessler, Udo Oppermann

Research output: Contribution to journal › Comment / Debate › Other › peer-review

1 Citation (Scopus)

Abstract

In Figure 5A, the chemical structure is incorrect. As a result, the Figure legend, “AOC3 inhibitor PXS-4681A shows analgesic effects in the endometriosis inoculation mouse model. (A) Structure of AOC3 inhibitor PXS-4681A, orally administered BID at 2 mg/kg. (B) Unbound plasma levels of PXS-4681A (at 1-2-4 mg/kg). (C) Target engagement results (2 mg/kg). (D) Changes in H2O2 in plasma. (E) Plasma exposure of PXS-4681A at day 2. (F) Front/rear paw ratio measure using the dynamic weight bearing system indicating reduction of pain behaviour under treatment.” should read: “AOC3 inhibitor PXS-4681A shows analgesic effects in the endometriosis inoculation mouse model. (A) Structure of AOC3 inhibitor PXS-4681A, orally administered BID at 2 mg/kg. The compound was synthesized according to literature procedures37 (B) Unbound plasma levels of PXS-4681A (at 1-2-4 mg/kg). (C) Target engagement results (2 mg/kg). (D) Changes in H2O2 in plasma. (E) Plasma exposure of PXS-4681A at day 2. (F) Front/rear paw ratio measure using the dynamic weight bearing system indicating reduction of pain behaviour under treatment.” The correct Figure 5 and its accompanying legend appear below as Figure 1.

Original language	English
Article number	5665
Number of pages	2
Journal	Scientific Reports
Volume	10
Issue number	1
DOIs	https://doi.org/10.1038/s41598-020-62492-z
Publication status	Published - 1 Dec 2020
Externally published	Yes

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10.1038/s41598-020-62492-z

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Thézénas, M. L., De Leo, B., Laux-Biehlmann, A., Bafligil, C., Elger, B., Tapmeier, T., Morten, K., Rahmioglu, N., Dakin, S. G., Charles, P., Martinez, F. E., Steers, G., Fischer, O. M., Mueller, J., Hess-Stumpp, H., Steinmeyer, A., Manek, S., Zondervan, K. T., Kennedy, S. H., ... Oppermann, U. (2020). Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions (Scientific Reports, (2020), 10, 1, (1495), 10.1038/s41598-020-58362-3). Scientific Reports, 10(1), Article 5665. https://doi.org/10.1038/s41598-020-62492-z

@article{349a9df74f4d482fa1b4ca9c6efac049,

title = "Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions (Scientific Reports, (2020), 10, 1, (1495), 10.1038/s41598-020-58362-3)",

abstract = "In Figure 5A, the chemical structure is incorrect. As a result, the Figure legend, “AOC3 inhibitor PXS-4681A shows analgesic effects in the endometriosis inoculation mouse model. (A) Structure of AOC3 inhibitor PXS-4681A, orally administered BID at 2 mg/kg. (B) Unbound plasma levels of PXS-4681A (at 1-2-4 mg/kg). (C) Target engagement results (2 mg/kg). (D) Changes in H2O2 in plasma. (E) Plasma exposure of PXS-4681A at day 2. (F) Front/rear paw ratio measure using the dynamic weight bearing system indicating reduction of pain behaviour under treatment.” should read: “AOC3 inhibitor PXS-4681A shows analgesic effects in the endometriosis inoculation mouse model. (A) Structure of AOC3 inhibitor PXS-4681A, orally administered BID at 2 mg/kg. The compound was synthesized according to literature procedures37 (B) Unbound plasma levels of PXS-4681A (at 1-2-4 mg/kg). (C) Target engagement results (2 mg/kg). (D) Changes in H2O2 in plasma. (E) Plasma exposure of PXS-4681A at day 2. (F) Front/rear paw ratio measure using the dynamic weight bearing system indicating reduction of pain behaviour under treatment.” The correct Figure 5 and its accompanying legend appear below as Figure 1.",

author = "Th{\'e}z{\'e}nas, {Marie La{\"e}titia} and {De Leo}, Bianca and Alexis Laux-Biehlmann and Cemsel Bafligil and Bernd Elger and Thomas Tapmeier and Karl Morten and Nilufer Rahmioglu and Dakin, {Stephanie G.} and Philip Charles and Martinez, {Fernando Estrada} and Graham Steers and Fischer, {Oliver M.} and Joerg Mueller and Holger Hess-Stumpp and Andreas Steinmeyer and Sanjiv Manek and Zondervan, {Krina T.} and Kennedy, {Stephen H} and Becker, {Christian M.} and Catherine Shang and Zollner, {Thomas M.} and Kessler, {Benedikt M.} and Udo Oppermann",

year = "2020",

month = dec,

day = "1",

doi = "10.1038/s41598-020-62492-z",

language = "English",

volume = "10",

journal = "Scientific Reports",

issn = "2045-2322",

publisher = "Nature Publishing Group",

number = "1",

}

Thézénas, ML, De Leo, B, Laux-Biehlmann, A, Bafligil, C, Elger, B, Tapmeier, T, Morten, K, Rahmioglu, N, Dakin, SG, Charles, P, Martinez, FE, Steers, G, Fischer, OM, Mueller, J, Hess-Stumpp, H, Steinmeyer, A, Manek, S, Zondervan, KT, Kennedy, SH, Becker, CM, Shang, C, Zollner, TM, Kessler, BM & Oppermann, U 2020, 'Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions (Scientific Reports, (2020), 10, 1, (1495), 10.1038/s41598-020-58362-3)', Scientific Reports, vol. 10, no. 1, 5665. https://doi.org/10.1038/s41598-020-62492-z

Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions (Scientific Reports, (2020), 10, 1, (1495), 10.1038/s41598-020-58362-3). / Thézénas, Marie Laëtitia; De Leo, Bianca; Laux-Biehlmann, Alexis et al.
In: Scientific Reports, Vol. 10, No. 1, 5665, 01.12.2020.

Research output: Contribution to journal › Comment / Debate › Other › peer-review

TY - JOUR

T1 - Author Correction

T2 - Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions (Scientific Reports, (2020), 10, 1, (1495), 10.1038/s41598-020-58362-3)

AU - Thézénas, Marie Laëtitia

AU - De Leo, Bianca

AU - Laux-Biehlmann, Alexis

AU - Bafligil, Cemsel

AU - Elger, Bernd

AU - Tapmeier, Thomas

AU - Morten, Karl

AU - Rahmioglu, Nilufer

AU - Dakin, Stephanie G.

AU - Charles, Philip

AU - Martinez, Fernando Estrada

AU - Steers, Graham

AU - Fischer, Oliver M.

AU - Mueller, Joerg

AU - Hess-Stumpp, Holger

AU - Steinmeyer, Andreas

AU - Manek, Sanjiv

AU - Zondervan, Krina T.

AU - Kennedy, Stephen H

AU - Becker, Christian M.

AU - Shang, Catherine

AU - Zollner, Thomas M.

AU - Kessler, Benedikt M.

AU - Oppermann, Udo

PY - 2020/12/1

Y1 - 2020/12/1

N2 - In Figure 5A, the chemical structure is incorrect. As a result, the Figure legend, “AOC3 inhibitor PXS-4681A shows analgesic effects in the endometriosis inoculation mouse model. (A) Structure of AOC3 inhibitor PXS-4681A, orally administered BID at 2 mg/kg. (B) Unbound plasma levels of PXS-4681A (at 1-2-4 mg/kg). (C) Target engagement results (2 mg/kg). (D) Changes in H2O2 in plasma. (E) Plasma exposure of PXS-4681A at day 2. (F) Front/rear paw ratio measure using the dynamic weight bearing system indicating reduction of pain behaviour under treatment.” should read: “AOC3 inhibitor PXS-4681A shows analgesic effects in the endometriosis inoculation mouse model. (A) Structure of AOC3 inhibitor PXS-4681A, orally administered BID at 2 mg/kg. The compound was synthesized according to literature procedures37 (B) Unbound plasma levels of PXS-4681A (at 1-2-4 mg/kg). (C) Target engagement results (2 mg/kg). (D) Changes in H2O2 in plasma. (E) Plasma exposure of PXS-4681A at day 2. (F) Front/rear paw ratio measure using the dynamic weight bearing system indicating reduction of pain behaviour under treatment.” The correct Figure 5 and its accompanying legend appear below as Figure 1.

AB - In Figure 5A, the chemical structure is incorrect. As a result, the Figure legend, “AOC3 inhibitor PXS-4681A shows analgesic effects in the endometriosis inoculation mouse model. (A) Structure of AOC3 inhibitor PXS-4681A, orally administered BID at 2 mg/kg. (B) Unbound plasma levels of PXS-4681A (at 1-2-4 mg/kg). (C) Target engagement results (2 mg/kg). (D) Changes in H2O2 in plasma. (E) Plasma exposure of PXS-4681A at day 2. (F) Front/rear paw ratio measure using the dynamic weight bearing system indicating reduction of pain behaviour under treatment.” should read: “AOC3 inhibitor PXS-4681A shows analgesic effects in the endometriosis inoculation mouse model. (A) Structure of AOC3 inhibitor PXS-4681A, orally administered BID at 2 mg/kg. The compound was synthesized according to literature procedures37 (B) Unbound plasma levels of PXS-4681A (at 1-2-4 mg/kg). (C) Target engagement results (2 mg/kg). (D) Changes in H2O2 in plasma. (E) Plasma exposure of PXS-4681A at day 2. (F) Front/rear paw ratio measure using the dynamic weight bearing system indicating reduction of pain behaviour under treatment.” The correct Figure 5 and its accompanying legend appear below as Figure 1.

UR - http://www.scopus.com/inward/record.url?scp=85082196816&partnerID=8YFLogxK

U2 - 10.1038/s41598-020-62492-z

DO - 10.1038/s41598-020-62492-z

M3 - Comment / Debate

C2 - 32205848

AN - SCOPUS:85082196816

SN - 2045-2322

VL - 10

JO - Scientific Reports

JF - Scientific Reports

IS - 1

M1 - 5665

ER -

Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions (Scientific Reports, (2020), 10, 1, (1495), 10.1038/s41598-020-58362-3)

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Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions

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