Augmented cardiovascular responses to episodes of repetitive compared with isolated respiratory events in preschool children with sleep-disordered breathing

Lisa Mary Walter, Sarah Nichole Biggs, Lauren Nisbet, Aidan Weichard, Milou Muntinga, Margot J Davey, Vicki Anne Anderson, Gillian Michelle Nixon, Rosemary Sylvia Claire Horne

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Childhood sleep disordered breathing presents as isolated respiratory events or episodes of consecutive repetitive events. We hypothesized that the surge in blood pressure (BP) and heart rate (HR) would be greater at the termination of events during episodes of repetitive events than following isolated events. METHODS: change in HR and pulse transit time (PTT; inverse surrogate of BP) were calculated from the last half of an event to: (i) between successive repetitive events; (ii) termination of the last repetitive event; (iii) event termination for isolated events. RESULTS: 69 of the children exhibiting both isolated and repetitive events had more repetitive than isolated events. HR change between repetitive events (27+/-1 ) was greater than at event termination for isolated events (17+/-1 ; p
Original languageEnglish
Pages (from-to)560 - 566
Number of pages7
JournalPediatric Research
Volume78
Issue number5
DOIs
Publication statusPublished - 2015

Cite this

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title = "Augmented cardiovascular responses to episodes of repetitive compared with isolated respiratory events in preschool children with sleep-disordered breathing",
abstract = "Childhood sleep disordered breathing presents as isolated respiratory events or episodes of consecutive repetitive events. We hypothesized that the surge in blood pressure (BP) and heart rate (HR) would be greater at the termination of events during episodes of repetitive events than following isolated events. METHODS: change in HR and pulse transit time (PTT; inverse surrogate of BP) were calculated from the last half of an event to: (i) between successive repetitive events; (ii) termination of the last repetitive event; (iii) event termination for isolated events. RESULTS: 69 of the children exhibiting both isolated and repetitive events had more repetitive than isolated events. HR change between repetitive events (27+/-1 ) was greater than at event termination for isolated events (17+/-1 ; p",
author = "Walter, {Lisa Mary} and Biggs, {Sarah Nichole} and Lauren Nisbet and Aidan Weichard and Milou Muntinga and Davey, {Margot J} and Anderson, {Vicki Anne} and Nixon, {Gillian Michelle} and Horne, {Rosemary Sylvia Claire}",
year = "2015",
doi = "10.1038/pr.2015.147",
language = "English",
volume = "78",
pages = "560 -- 566",
journal = "Pediatric Research",
issn = "0031-3998",
publisher = "Nature Publishing Group",
number = "5",

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TY - JOUR

T1 - Augmented cardiovascular responses to episodes of repetitive compared with isolated respiratory events in preschool children with sleep-disordered breathing

AU - Walter, Lisa Mary

AU - Biggs, Sarah Nichole

AU - Nisbet, Lauren

AU - Weichard, Aidan

AU - Muntinga, Milou

AU - Davey, Margot J

AU - Anderson, Vicki Anne

AU - Nixon, Gillian Michelle

AU - Horne, Rosemary Sylvia Claire

PY - 2015

Y1 - 2015

N2 - Childhood sleep disordered breathing presents as isolated respiratory events or episodes of consecutive repetitive events. We hypothesized that the surge in blood pressure (BP) and heart rate (HR) would be greater at the termination of events during episodes of repetitive events than following isolated events. METHODS: change in HR and pulse transit time (PTT; inverse surrogate of BP) were calculated from the last half of an event to: (i) between successive repetitive events; (ii) termination of the last repetitive event; (iii) event termination for isolated events. RESULTS: 69 of the children exhibiting both isolated and repetitive events had more repetitive than isolated events. HR change between repetitive events (27+/-1 ) was greater than at event termination for isolated events (17+/-1 ; p

AB - Childhood sleep disordered breathing presents as isolated respiratory events or episodes of consecutive repetitive events. We hypothesized that the surge in blood pressure (BP) and heart rate (HR) would be greater at the termination of events during episodes of repetitive events than following isolated events. METHODS: change in HR and pulse transit time (PTT; inverse surrogate of BP) were calculated from the last half of an event to: (i) between successive repetitive events; (ii) termination of the last repetitive event; (iii) event termination for isolated events. RESULTS: 69 of the children exhibiting both isolated and repetitive events had more repetitive than isolated events. HR change between repetitive events (27+/-1 ) was greater than at event termination for isolated events (17+/-1 ; p

UR - http://www.nature.com/pr/journal/v78/n5/pdf/pr2015147a.pdf

U2 - 10.1038/pr.2015.147

DO - 10.1038/pr.2015.147

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VL - 78

SP - 560

EP - 566

JO - Pediatric Research

JF - Pediatric Research

SN - 0031-3998

IS - 5

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