Atypical interference control in children with AD/HD with elevated theta/beta ratio

Da Wei Zhang, Steven Roodenrys, Hui Li, Robert J. Barry, Adam R. Clarke, Zhanliang Wu, Qihua Zhao, Yan Song, Lu Liu, Qiujin Qian, Yufeng Wang, Stuart J. Johnstone, Li Sun

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Abstract

The theta/beta ratio (TBR) is a major area of interest within electroencephalogram (EEG) research in AD/HD. While researchers suggest a prognostic role for TBR in AD/HD, its relationship to behavior remains uncertain. Recent evidence suggests that elevated TBR in AD/HD may be related to atypical inhibition, particularly at an attentional level. This study aimed to examine the performance on three inhibitory tasks of children with AD/HD. Fifty-eight children with AD/HD participated, divided into an elevated TBR (ET) group and a control group (CT). A behavioral disassociation was found − compared to CT, ET showed more difficulty in inhibiting surrounding stimuli but had less day-to-day inhibitory issues measured by BRIEF. There was no significant group difference on response inhibition. The results support the prognostic value of TBR in AD/HD. Elevated TBR may be an inhibitory biomarker; further studies are needed to explore the behavioral implications in patients without elevated TBR.

Original languageEnglish
Pages (from-to)82-88
Number of pages7
JournalBiological Psychology
Volume128
DOIs
Publication statusPublished - Sept 2017
Externally publishedYes

Keywords

  • AD/HD
  • Biomarker
  • EEG
  • Inhibition
  • Interference control
  • Theta/beta ratio

Cite this