TY - JOUR
T1 - Atrial electrical and structural abnormalities in an ovine model of chronic blood pressure elevation after prenatal corticosteroid exposure: Implications for development of atrial fibrillation
AU - Kistler, Peter
AU - Sanders, Prashanthan
AU - Dodic, Miodrag
AU - Spence, Steven
AU - Samuel, Chrishan
AU - Zhao, Chongxin
AU - Charles, Jennifer
AU - Edwards, Glenn
AU - Kalman, Johnathon
PY - 2006
Y1 - 2006
N2 - AIMS: Elevated blood pressure (EBP) is the most prevalent and potentially modifiable risk factor for AF, yet little is known of its atrial effects. We aimed to characterize the atrial electrical and structural changes in a chronic ovine model of EBP after prenatal corticosteroid exposure. METHODS AND RESULTS: Twelve sheep with chronically EBP (mean arterial pressure 94+/-3 mmHg) and six controls (71+/-4 mmHg, P
AB - AIMS: Elevated blood pressure (EBP) is the most prevalent and potentially modifiable risk factor for AF, yet little is known of its atrial effects. We aimed to characterize the atrial electrical and structural changes in a chronic ovine model of EBP after prenatal corticosteroid exposure. METHODS AND RESULTS: Twelve sheep with chronically EBP (mean arterial pressure 94+/-3 mmHg) and six controls (71+/-4 mmHg, P
UR - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17098760
U2 - 10.1093/eurheartj/ehl360
DO - 10.1093/eurheartj/ehl360
M3 - Article
SN - 0195-668X
VL - 27
SP - 3045
EP - 3056
JO - European Heart Journal
JF - European Heart Journal
IS - 24
ER -