At a glance: Cellular biology for engineers

Khashayar Khoshmanesh, Abbas Z Kouzani, Saeid Nahavandi, Sara Baratchi, Jagat R Kanwar

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Abstract

Engineering contributions have played an important role in the rise and evolution of cellular biology. Engineering technologies have helped biologists to explore the living organisms at cellular and molecular levels, and have created new opportunities to tackle the unsolved biological problems. There is now a growing demand to further expand the role of engineering in cellular biology research. For an engineer to play an effective role in cellular biology, the first essential step is to understand the cells and their components. However, the stumbling block of this step is to comprehend the information given in the cellular biology literature because it best suits the readers with a biological background. This paper aims to overcome this bottleneck by describing the human cell components as micro-plants that form cells as micro-bio-factories. This concept can accelerate the engineers comprehension of the subject. In this paper, first the structure and function of different cell components are described. In addition, the engineering attempts to mimic various cell components through numerical modelling or physical implementation are highlighted. Next, the interaction of different cell components that facilitate complicated chemical processes, such as energy generation and protein synthesis, are described. These complex interactions are translated into simple flow diagrams, generally used by engineers to represent multi-component processes.
Original languageEnglish
Pages (from-to)315 - 331
Number of pages17
JournalComputational Biology and Chemistry
Volume32
Issue number5
DOIs
Publication statusPublished - 2008
Externally publishedYes

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