Asymmetric Arylation of Imines Catalyzed by Heterogeneous Chiral Rhodium Nanoparticles

Tomohiro Yasukawa, Tatsuya Kuremoto, Hiroyuki Miyamura, Shų Kobayashi

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Abstract

Asymmetric arylation of aldimines catalyzed by heterogeneous chiral rhodium nanoparticles has been developed. The reaction proceeded in aqueous media without significant decomposition of the imines by hydrolysis to afford chiral (diarylmethyl)amines in high yields with outstanding enantioselectivities. This catalyst system exhibited the highest turnover number (700) in heterogeneous catalysts reported to date for these reactions. The reusability of the catalyst was also demonstrated.

Original languageEnglish
Pages (from-to)2716-2718
Number of pages3
JournalOrganic Letters
Volume18
Issue number11
DOIs
Publication statusPublished - 3 Jun 2016
Externally publishedYes

Cite this