Asthma drugs in pregnancy and lactation

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Abstract

Uncontrolled asthma during pregnancy poses many short and long-term risks to the mother and her baby. Maintaining optimal asthma control is important during pregnancy, but studies of drug safety are limited. Inhaled short-acting beta agonists are safe to prescribe throughout pregnancy. Long-acting beta agonists need not be stopped in the first trimester and can be used in the second and third trimesters if needed to maintain adequate asthma control. Inhaled corticosteroids, particularly budesonide, at recommended doses are safe to use during pregnancy and breastfeeding. Oral corticosteroids, at the doses used to treat asthma exacerbations, do not appear to pose a significant risk to the mother or child. Pregnant women tend to overestimate the risk of using asthma drugs, but they are often unaware of the greater risks of uncontrolled asthma. They put themselves at unnecessary risk of acute exacerbations by discontinuing or reducing therapy. Women with asthma should be advised to continue to take their treatment while breastfeeding. Spacing the dose and feed time may be necessary when using oral corticosteroids.
Original languageEnglish
Pages (from-to)150 - 153
Number of pages4
JournalAustralian Prescriber
Volume36
Issue number5
DOIs
Publication statusPublished - 2013

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