Associations of long-term exposure to ambient PM 1 with hypertension and blood pressure in rural Chinese population: The Henan rural cohort study

Na Li, Gongbo Chen, Feifei Liu, Shuyuan Mao, Yisi Liu, Yitan Hou, Yuanan Lu, Suyang Liu, Chongjian Wang, Hao Xiang, Yuming Guo, Shanshan Li

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26 Citations (Scopus)

Abstract

Background: The epidemiological evidence on relationships between long-term exposure to particulate matter and hypertension and blood pressure has been inconclusive. Limited evidence was available for particulate matter with an aerodynamic diameter ≤ 1 μm (PM 1 )in rural areas of developing countries. Objective: This study aimed to investigate the associations between long-term exposure to PM 1 and hypertension and blood pressure among rural Chinese population. Methods: This study included 39,259 participants who had completed the baseline survey from Henan Rural Cohort. Participants' exposure to PM 1 was assessed by a satellite-based spatiotemporal model. The binary logistic regression model was used to examine the association between long-term PM 1 exposure and hypertension, and multivariable linear regression model was used to investigate the associations between long-term PM 1 exposure and systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP)and pulse pressure (PP). Moreover, we examined potential effect modifications by demographic, lifestyle and diet factors. Results: The mean concentration of PM 1 for all participants during the 3-year before baseline survey was 59.98 μg/m 3 . Each 1 μg/m 3 increase in PM 1 concentration was significantly associated with an increase of 4.3% [Odds ratio(OR)= 1.043, 95% confidence interval(CI): 1.033, 1.053]in odds for hypertension, an increase of 0.401 mm Hg (95% CI, 0.335, 0.467), 0.328 mm Hg (95% CI, 0.288, 0.369), 0.353 mm Hg (95% CI, 0.307, 0.399)and 0.073 mm Hg (95% CI, 0.030, 0.116)in SBP, DBP, MAP and PP, respectively. Further stratified analyses showed that the effect of PM 1 on hypertension and blood pressure could be modified by sex, lifestyle and diet. Conclusions: This study suggests that long-term exposure to ambient PM 1 increases the risk of hypertension and is associated with elevations in blood pressure in rural Chinese adults, especially in male and those with unhealthy habits.

Original languageEnglish
Pages (from-to)95-102
Number of pages8
JournalEnvironment International
Volume128
DOIs
Publication statusPublished - Jul 2019

Keywords

  • Air pollution
  • Blood pressure
  • Hypertension
  • PM
  • Rural China

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