Associations of ambient particulate matter with homocysteine metabolism markers and effect modification by B vitamins and MTHFR C677T gene polymorphism

Bo Yi Yang; Ke Cao; Ya Na Luo; Zhi Zhou He; Peng Yue Guo; Hui Min Ma; Mo Yang; Yang Zhou; Li Wen Hu; Gong Bo Chen; Xiao Wen Zeng; Hong Yao Yu; Yunjiang Yu; Guang Hui Dong

doi:10.1016/j.envpol.2020.116211

Associations of ambient particulate matter with homocysteine metabolism markers and effect modification by B vitamins and MTHFR C677T gene polymorphism

Bo Yi Yang, Ke Cao, Ya Na Luo, Zhi Zhou He, Peng Yue Guo, Hui Min Ma, Mo Yang, Yang Zhou, Li Wen Hu, Gong Bo Chen, Xiao Wen Zeng, Hong Yao Yu, Yunjiang Yu, Guang Hui Dong

Research output: Contribution to journal › Article › Research › peer-review

8 Citations (Scopus)

Abstract

Short-term exposures to PM_2.5 and PM_1.0 were deleteriously associated with the HCY metabolism markers, and the associations were modified by B vitamins.

Original language	English
Article number	116211
Number of pages	9
Journal	Environmental Pollution
Volume	270
DOIs	https://doi.org/10.1016/j.envpol.2020.116211
Publication status	Published - 1 Feb 2021
Externally published	Yes

Keywords

B vitamin
Homocysteine
Methylenetetrahyfrofolate reductase
Particulate matter

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10.1016/j.envpol.2020.116211

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Yang, B. Y., Cao, K., Luo, Y. N., He, Z. Z., Guo, P. Y., Ma, H. M., Yang, M., Zhou, Y., Hu, L. W., Chen, G. B., Zeng, X. W., Yu, H. Y., Yu, Y., & Dong, G. H. (2021). Associations of ambient particulate matter with homocysteine metabolism markers and effect modification by B vitamins and MTHFR C677T gene polymorphism. Environmental Pollution, 270, Article 116211. https://doi.org/10.1016/j.envpol.2020.116211

@article{a3e6eee69c17461ca51149d5bd15aafb,

title = "Associations of ambient particulate matter with homocysteine metabolism markers and effect modification by B vitamins and MTHFR C677T gene polymorphism",

abstract = "Short-term exposures to PM2.5 and PM1.0 were deleteriously associated with the HCY metabolism markers, and the associations were modified by B vitamins.",

keywords = "B vitamin, Homocysteine, Methylenetetrahyfrofolate reductase, Particulate matter",

author = "Yang, \{Bo Yi\} and Ke Cao and Luo, \{Ya Na\} and He, \{Zhi Zhou\} and Guo, \{Peng Yue\} and Ma, \{Hui Min\} and Mo Yang and Yang Zhou and Hu, \{Li Wen\} and Chen, \{Gong Bo\} and Zeng, \{Xiao Wen\} and Yu, \{Hong Yao\} and Yunjiang Yu and Dong, \{Guang Hui\}",

note = "Funding Information: This study was supported by National Natural Science Foundation of China (No. 81703179 ; No. 81673139 ; No. 81972992 ; No. 91543208 ; No. 81803196 ; No. 81673128 ; No. 81872582 ) and Science and Technology Program of Guangzhou, China (No. 202002030440 ). The authors acknowledge the cooperation of participants in this study who have been very generous with their time and assistance. Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",

year = "2021",

month = feb,

day = "1",

doi = "10.1016/j.envpol.2020.116211",

language = "English",

volume = "270",

journal = "Environmental Pollution",

issn = "0269-7491",

publisher = "Elsevier",

}

Yang, BY, Cao, K, Luo, YN, He, ZZ, Guo, PY, Ma, HM, Yang, M, Zhou, Y, Hu, LW, Chen, GB, Zeng, XW, Yu, HY, Yu, Y & Dong, GH 2021, 'Associations of ambient particulate matter with homocysteine metabolism markers and effect modification by B vitamins and MTHFR C677T gene polymorphism', Environmental Pollution, vol. 270, 116211. https://doi.org/10.1016/j.envpol.2020.116211

TY - JOUR

T1 - Associations of ambient particulate matter with homocysteine metabolism markers and effect modification by B vitamins and MTHFR C677T gene polymorphism

AU - Yang, Bo Yi

AU - Cao, Ke

AU - Luo, Ya Na

AU - He, Zhi Zhou

AU - Guo, Peng Yue

AU - Ma, Hui Min

AU - Yang, Mo

AU - Zhou, Yang

AU - Hu, Li Wen

AU - Chen, Gong Bo

AU - Zeng, Xiao Wen

AU - Yu, Hong Yao

AU - Yu, Yunjiang

AU - Dong, Guang Hui

N1 - Funding Information: This study was supported by National Natural Science Foundation of China (No. 81703179 ; No. 81673139 ; No. 81972992 ; No. 91543208 ; No. 81803196 ; No. 81673128 ; No. 81872582 ) and Science and Technology Program of Guangzhou, China (No. 202002030440 ). The authors acknowledge the cooperation of participants in this study who have been very generous with their time and assistance. Publisher Copyright: © 2020 Elsevier Ltd

PY - 2021/2/1

Y1 - 2021/2/1

N2 - Short-term exposures to PM2.5 and PM1.0 were deleteriously associated with the HCY metabolism markers, and the associations were modified by B vitamins.

AB - Short-term exposures to PM2.5 and PM1.0 were deleteriously associated with the HCY metabolism markers, and the associations were modified by B vitamins.

KW - B vitamin

KW - Homocysteine

KW - Methylenetetrahyfrofolate reductase

KW - Particulate matter

UR - https://www.scopus.com/pages/publications/85097754822

U2 - 10.1016/j.envpol.2020.116211

DO - 10.1016/j.envpol.2020.116211

M3 - Article

C2 - 33348139

AN - SCOPUS:85097754822

SN - 0269-7491

VL - 270

JO - Environmental Pollution

JF - Environmental Pollution

M1 - 116211

ER -

Associations of ambient particulate matter with homocysteine metabolism markers and effect modification by B vitamins and MTHFR C677T gene polymorphism

Abstract

Keywords

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