Association of PCOS and its clinical signs with sexual function among iranian women affected by PCOS

Introduction: Polycystic ovary syndrome (PCOS) and its physiological and psychological changes influence the sexual function of women affected. Aim: In the present study, we aimed to investigate the association of PCOS and its clinical signs with sexual function among a population of married Iranian women affected by PCOS. Main Outcome Measure: The impact of clinical signs of PCOS on sexual function of affected women was the main outcome measure in the present study. Methods: This cross-sectional study was carried out on 591 married women with PCOS, aged 18-45 years. Data were collected using a questionnaire including information on demographic and reproductive status and the Female Sexual Function Index. Data were analyzed using chi-square test, Mann-Whitney test, and logistic regression analysis. Results: The participants' mean age was 30.6 years. Among associated manifestations of PCOS, infertility and hair loss have significant adverse effects on female sexual function. Logistic regression analysis showed that PCOS women with infertility have a significantly lower sexual function score compared with those who are fertile. Subgroup analysis demonstrated that compared with their fertile counterparts, PCOS women with infertility had significant sexual dysfunction in all aspects except desire and pain. Conclusion: Among various manifestations of PCOS, infertility mainly disrupts the sexual function of affected women.