Association between hip and knee cartilage measured using radiographs and magnetic resonance imaging: the Tasmanian Older Adult Cohort Study

Hussain I Khan, Dawn Aitken, Guangju Zhai, Changhai Ding, Jean-Pierre Pelletier, Johanne Martel Pelletier, Flavia Maria Cicuttini, Leigh Blizzard, Graeme Jones

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4 Citations (Scopus)

Abstract

Cartilage loss is a key pathological feature of OA and can be assessed indirectly using radiography or directly through MRI. A number of cross-sectional studies have suggested that primary generalized osteoarthritis (PGOA) may be a distinct disease, but despite the high frequency of involvement of the hip and the knee joints in OA, very few studies have looked at the radiographic association between these two joints, and none has done so using MRI. The aim of this study was to examine the association of hip and knee cartilage measured by both radiography and MRI. Methods. We studied 151 participants from the Tasmanian Older Adult Cohort (TASOAC) study, who were selected randomly from the southern Tasmanian electoral rolls. MRI was used to assess hip and knee cartilage volume and radiography was used to assess joint space narrowing (JSN). Correlation analyses were used to compare cartilage volume measurements and JSN. Results. In adjusted analysis, there was a consistent, positive association between knee and hip cartilage volume that was best for total knee cartilage volume (r = 0.16-0.40, all P
Original languageEnglish
Pages (from-to)2009 - 2015
Number of pages7
JournalRheumatology
Volume52
Issue number11
DOIs
Publication statusPublished - 2013

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