Association between dietary intake and lipid-lowering therapy

Prospective analysis of data from australian diabetes, obesity, and lifestyle study (aus diab) using a quantile regression approach

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Lipid-lowering therapy (LLT) should be accompanied by dietary guidance for cardiovascular risk reduction; however, current evidence suggests sub-optimal dietary behaviors in those on LLT. We examined the associations between the dietary intake of key food groups (vegetables, fruit, cereal, protein, and dairy) and LLT use in Australian adults using quantile regression. We used data from the Australian Diabetes, Obesity and Lifestyle Study (Aus Diab), a prospective population-based study of adults aged ≥25 years, conducted over 5 years (1999–2005). Measurements included a 121-item food frequency questionnaire and LLT use. LLT use was categorized as: LLT users (n = 446), commenced LLT (n = 565), ceased LLT (n = 71), and non-users (n = 4813). Less than 1% of the cohort met recommended intakes of all food groups at the baseline and follow up. The median daily dietary intake at the follow up among LLT users was 2.2 serves of vegetables, 1.4 serves of fruit, 2.8 serves of cereal, 2.0 serves of protein, and 1.4 serves of dairy. Adjusted analysis showed no differences across the quantiles of intake of key food groups in LLT users and commenced LLT compared to non-users. The LLT medication status is not associated with any difference in meeting recommended intakes of key foods.

Original languageEnglish
Article number1858
Number of pages13
JournalNutrients
Volume11
Issue number8
DOIs
Publication statusPublished - 1 Aug 2019

Keywords

  • Cardiovascular disease
  • Cereal
  • Dairy
  • Food groups
  • Fruit
  • Lipid-lowering therapy
  • Protein
  • Quantile regression
  • Statins
  • Vegetable

Cite this

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title = "Association between dietary intake and lipid-lowering therapy: Prospective analysis of data from australian diabetes, obesity, and lifestyle study (aus diab) using a quantile regression approach",
abstract = "Lipid-lowering therapy (LLT) should be accompanied by dietary guidance for cardiovascular risk reduction; however, current evidence suggests sub-optimal dietary behaviors in those on LLT. We examined the associations between the dietary intake of key food groups (vegetables, fruit, cereal, protein, and dairy) and LLT use in Australian adults using quantile regression. We used data from the Australian Diabetes, Obesity and Lifestyle Study (Aus Diab), a prospective population-based study of adults aged ≥25 years, conducted over 5 years (1999–2005). Measurements included a 121-item food frequency questionnaire and LLT use. LLT use was categorized as: LLT users (n = 446), commenced LLT (n = 565), ceased LLT (n = 71), and non-users (n = 4813). Less than 1{\%} of the cohort met recommended intakes of all food groups at the baseline and follow up. The median daily dietary intake at the follow up among LLT users was 2.2 serves of vegetables, 1.4 serves of fruit, 2.8 serves of cereal, 2.0 serves of protein, and 1.4 serves of dairy. Adjusted analysis showed no differences across the quantiles of intake of key food groups in LLT users and commenced LLT compared to non-users. The LLT medication status is not associated with any difference in meeting recommended intakes of key foods.",
keywords = "Cardiovascular disease, Cereal, Dairy, Food groups, Fruit, Lipid-lowering therapy, Protein, Quantile regression, Statins, Vegetable",
author = "Gadowski, {Adelle M.} and Natalie Nanayakkara and Stephane Heritier and Magliano, {Dianna J.} and Shaw, {Jonathan E.} and Curtis, {Andrea J.} and Sophia Zoungas and Owen, {Alice J.}",
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T2 - Prospective analysis of data from australian diabetes, obesity, and lifestyle study (aus diab) using a quantile regression approach

AU - Gadowski, Adelle M.

AU - Nanayakkara, Natalie

AU - Heritier, Stephane

AU - Magliano, Dianna J.

AU - Shaw, Jonathan E.

AU - Curtis, Andrea J.

AU - Zoungas, Sophia

AU - Owen, Alice J.

PY - 2019/8/1

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N2 - Lipid-lowering therapy (LLT) should be accompanied by dietary guidance for cardiovascular risk reduction; however, current evidence suggests sub-optimal dietary behaviors in those on LLT. We examined the associations between the dietary intake of key food groups (vegetables, fruit, cereal, protein, and dairy) and LLT use in Australian adults using quantile regression. We used data from the Australian Diabetes, Obesity and Lifestyle Study (Aus Diab), a prospective population-based study of adults aged ≥25 years, conducted over 5 years (1999–2005). Measurements included a 121-item food frequency questionnaire and LLT use. LLT use was categorized as: LLT users (n = 446), commenced LLT (n = 565), ceased LLT (n = 71), and non-users (n = 4813). Less than 1% of the cohort met recommended intakes of all food groups at the baseline and follow up. The median daily dietary intake at the follow up among LLT users was 2.2 serves of vegetables, 1.4 serves of fruit, 2.8 serves of cereal, 2.0 serves of protein, and 1.4 serves of dairy. Adjusted analysis showed no differences across the quantiles of intake of key food groups in LLT users and commenced LLT compared to non-users. The LLT medication status is not associated with any difference in meeting recommended intakes of key foods.

AB - Lipid-lowering therapy (LLT) should be accompanied by dietary guidance for cardiovascular risk reduction; however, current evidence suggests sub-optimal dietary behaviors in those on LLT. We examined the associations between the dietary intake of key food groups (vegetables, fruit, cereal, protein, and dairy) and LLT use in Australian adults using quantile regression. We used data from the Australian Diabetes, Obesity and Lifestyle Study (Aus Diab), a prospective population-based study of adults aged ≥25 years, conducted over 5 years (1999–2005). Measurements included a 121-item food frequency questionnaire and LLT use. LLT use was categorized as: LLT users (n = 446), commenced LLT (n = 565), ceased LLT (n = 71), and non-users (n = 4813). Less than 1% of the cohort met recommended intakes of all food groups at the baseline and follow up. The median daily dietary intake at the follow up among LLT users was 2.2 serves of vegetables, 1.4 serves of fruit, 2.8 serves of cereal, 2.0 serves of protein, and 1.4 serves of dairy. Adjusted analysis showed no differences across the quantiles of intake of key food groups in LLT users and commenced LLT compared to non-users. The LLT medication status is not associated with any difference in meeting recommended intakes of key foods.

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KW - Cereal

KW - Dairy

KW - Food groups

KW - Fruit

KW - Lipid-lowering therapy

KW - Protein

KW - Quantile regression

KW - Statins

KW - Vegetable

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