Assignments of human integrin a1I domain in the apo and Mg2+ bound states

Yanni Ka-Yan Chin, Stephen James Headey, Biswaranjan Mohanty, Jonas Emsley, Jamie Scott Simpson, Martin Scanlon

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

The a1?1 integrin receptor binds to its main extracellular ligand, collagen, through an inserted domain in its a-subunit called the aI domain (aI). aI contains a metal binding site that allows collagen to coordinate to the domain through a divalent metal ion. Here we report the backbone assignments of the apo and Mg2+ bound state of the isolated human a1I and the chemical shift changes resulting from metal coordination. ? 2013 Springer Science+Business Media Dordrecht.
Original languageEnglish
Pages (from-to)117 - 121
Number of pages5
JournalBiomolecular NMR Assignments
Volume8
Issue number1
DOIs
Publication statusPublished - 2014

Cite this

Chin, Yanni Ka-Yan ; Headey, Stephen James ; Mohanty, Biswaranjan ; Emsley, Jonas ; Simpson, Jamie Scott ; Scanlon, Martin. / Assignments of human integrin a1I domain in the apo and Mg2+ bound states. In: Biomolecular NMR Assignments. 2014 ; Vol. 8, No. 1. pp. 117 - 121.
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Assignments of human integrin a1I domain in the apo and Mg2+ bound states. / Chin, Yanni Ka-Yan; Headey, Stephen James; Mohanty, Biswaranjan; Emsley, Jonas; Simpson, Jamie Scott; Scanlon, Martin.

In: Biomolecular NMR Assignments, Vol. 8, No. 1, 2014, p. 117 - 121.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Chin, Yanni Ka-Yan

AU - Headey, Stephen James

AU - Mohanty, Biswaranjan

AU - Emsley, Jonas

AU - Simpson, Jamie Scott

AU - Scanlon, Martin

PY - 2014

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DO - 10.1007/s12104-013-9465-7

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