Assignments of human integrin a1I domain in the apo and Mg2+ bound states

Yanni Ka-Yan Chin, Stephen James Headey, Biswaranjan Mohanty, Jonas Emsley, Jamie Scott Simpson, Martin Scanlon

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4 Citations (Scopus)


The a1?1 integrin receptor binds to its main extracellular ligand, collagen, through an inserted domain in its a-subunit called the aI domain (aI). aI contains a metal binding site that allows collagen to coordinate to the domain through a divalent metal ion. Here we report the backbone assignments of the apo and Mg2+ bound state of the isolated human a1I and the chemical shift changes resulting from metal coordination. ? 2013 Springer Science+Business Media Dordrecht.
Original languageEnglish
Pages (from-to)117 - 121
Number of pages5
JournalBiomolecular NMR Assignments
Issue number1
Publication statusPublished - 2014

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