TY - JOUR
T1 - Assignments of human integrin a1I domain in the apo and Mg2+ bound states
AU - Chin, Yanni Ka-Yan
AU - Headey, Stephen James
AU - Mohanty, Biswaranjan
AU - Emsley, Jonas
AU - Simpson, Jamie Scott
AU - Scanlon, Martin
PY - 2014
Y1 - 2014
N2 - The a1?1 integrin receptor binds to its main extracellular ligand, collagen, through an inserted domain in its a-subunit called the aI domain (aI). aI contains a metal binding site that allows collagen to coordinate to the domain through a divalent metal ion. Here we report the backbone assignments of the apo and Mg2+ bound state of the isolated human a1I and the chemical shift changes resulting from metal coordination. ? 2013 Springer Science+Business Media Dordrecht.
AB - The a1?1 integrin receptor binds to its main extracellular ligand, collagen, through an inserted domain in its a-subunit called the aI domain (aI). aI contains a metal binding site that allows collagen to coordinate to the domain through a divalent metal ion. Here we report the backbone assignments of the apo and Mg2+ bound state of the isolated human a1I and the chemical shift changes resulting from metal coordination. ? 2013 Springer Science+Business Media Dordrecht.
UR - http://download.springer.com/static/pdf/438/art%253A10.1007%252Fs12104-013-9465-7.pdf?auth66=1423716150_c4889fc336190787d3d4f4d0d2d08e89&ext=.pdf
U2 - 10.1007/s12104-013-9465-7
DO - 10.1007/s12104-013-9465-7
M3 - Article
SN - 1874-2718
VL - 8
SP - 117
EP - 121
JO - Biomolecular NMR Assignments
JF - Biomolecular NMR Assignments
IS - 1
ER -