Assessment of synthetic 3T image generator for accurate CSF volume measurement in T1-w, T2-w, and FLAIR sequences compared to low-field imaging

Kh Tohidul Islam, Shenjun Zhong, Parisa Zakavi, Helen Kavnoudias, Shawna Farquharson, Gail Durbridge, Markus Barth, Katie L McMahon, Paul M. Parizel, Gary F. Egan, Andrew Dwyer, Meng Law, Zhaolin Chen

Research output: Contribution to conferenceAbstractpeer-review

Abstract

Motivation: Addressing limited access to high-field MRI systems, our study investigates whether a Synthetic 3T Image Generator can enhance low-field MRI to match high-field image quality, crucial for accurate cerebrospinal fluid (CSF) volume analysis. Goal(s): We aimed to validate the efficacy of the Synthetic 3T generator in improving CSF volume measurements on low-field MRI, in comparison to high-field T1-w, T2-w, and FLAIR sequences. Approach: A cGAN was employed to enhance 64mT MRI data to synthetic 3T images, for evaluation in comparison to high-field MRIs. Results: The synthetic 3T images demonstrated significant improvements in CSF volume estimation across all sequences when compared to low-field images. Impact: The synthetic 3T MRI enhancements could advance neuroimaging in resource-limited settings, improve diagnostic precision for brain injuries and potentially broaden the application of neurological and psychiatric patient care worldwide and expand neuroimaging research opportunities.
Original languageEnglish
Number of pages2
Publication statusPublished - May 2024
EventInternational Society for Magnetic Resonance in Medicine (ISMRM) & The International Society for MR Radiographers & Technologists (ISMRT) Annual Meeting & Exhibition 2024  - Suntec Singapore Convention & Exhibition Centre, Singapore
Duration: 4 May 20249 May 2024
https://www.ismrm.org/24m/

Exhibition

ExhibitionInternational Society for Magnetic Resonance in Medicine (ISMRM) & The International Society for MR Radiographers & Technologists (ISMRT) Annual Meeting & Exhibition 2024 
Abbreviated titleISMRM & ISMRT 2024
Country/TerritorySingapore
Period4/05/249/05/24
Internet address

Keywords

  • AI/ML Image Reconstruction
  • Low-Field MRI
  • 64mT

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