The 1,2,4-trisubstituted pyrrole (4), which is readily prepared from pyrrole itself, undergoes doublebarrelled Heck cyclizations to give, inter alia, compounds (3) and (17) for which crystal structures have been determined. Product (3) constitutes the core associated with several key members, e.g. (1) and (2), of the lamellarin class of marine alkaloid.
|Journal||Australian Journal of Chemistry|
|Publication status||Published - 1 Dec 1999|