Assessing mood and general health-related quality of life among men treated in Australia for localized prostate cancer

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Abstract

OBJECTIVE: Although increasing numbers of Australian men are undergoing treatment for localized prostate cancer (PCa), the health-related quality of life (HRQOL) of this patient cohort has received little research attention. We therefore compared the mood and general HRQOL of Australian localized PCa patients with a sample of untreated men. METHODS: A retrospective cross-sectional design was used to compare the longer-term positive and negative affect and general HRQOL of 82 radical prostatectomy (RP) cases, 39 external-beam radiation (EBRT), and 95 untreated comparison cases (CC). All PCa cases had undergone treatment more than 2 years prior to data collection. RESULTS: Levels of positive and negative affect did not differ with treatment modality. After adjusting for the variance attributable to age and comorbidity, RP, EBRT and CC group participants displayed similar general HRQOL profiles. Treatment dissatisfaction was higher among EBRT compared to RP cases (P = 0.024, two-tailed test). CONCLUSION: In the longer-term, mood did not vary significantly with PCa treatment. Furthermore, when age and comorbidity were taken into account, RP and EBRT patients had similar HRQOL profiles. While not statistically significant, the trend towards the importance of family, social and medical support among PCa patients requires further investigation.
Original languageEnglish
Pages (from-to)311-316
Number of pages6
JournalInternational Journal of Urology
Volume14
Issue number4
DOIs
Publication statusPublished - 2007

Cite this

@article{7d5c7f4cc3e245a58df57ce03e45318b,
title = "Assessing mood and general health-related quality of life among men treated in Australia for localized prostate cancer",
abstract = "OBJECTIVE: Although increasing numbers of Australian men are undergoing treatment for localized prostate cancer (PCa), the health-related quality of life (HRQOL) of this patient cohort has received little research attention. We therefore compared the mood and general HRQOL of Australian localized PCa patients with a sample of untreated men. METHODS: A retrospective cross-sectional design was used to compare the longer-term positive and negative affect and general HRQOL of 82 radical prostatectomy (RP) cases, 39 external-beam radiation (EBRT), and 95 untreated comparison cases (CC). All PCa cases had undergone treatment more than 2 years prior to data collection. RESULTS: Levels of positive and negative affect did not differ with treatment modality. After adjusting for the variance attributable to age and comorbidity, RP, EBRT and CC group participants displayed similar general HRQOL profiles. Treatment dissatisfaction was higher among EBRT compared to RP cases (P = 0.024, two-tailed test). CONCLUSION: In the longer-term, mood did not vary significantly with PCa treatment. Furthermore, when age and comorbidity were taken into account, RP and EBRT patients had similar HRQOL profiles. While not statistically significant, the trend towards the importance of family, social and medical support among PCa patients requires further investigation.",
author = "Newton, {Fiona Joy} and Sue Burney and Mark Frydenberg and Jeremy Millar and Ng, {Kim Tee}",
note = "Cited By :3 Export Date: 2 October 2016",
year = "2007",
doi = "10.1111{\%}2Fj.1442-2042.2006.01720.x",
language = "English",
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pages = "311--316",
journal = "International Journal of Urology",
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TY - JOUR

T1 - Assessing mood and general health-related quality of life among men treated in Australia for localized prostate cancer

AU - Newton, Fiona Joy

AU - Burney, Sue

AU - Frydenberg, Mark

AU - Millar, Jeremy

AU - Ng, Kim Tee

N1 - Cited By :3 Export Date: 2 October 2016

PY - 2007

Y1 - 2007

N2 - OBJECTIVE: Although increasing numbers of Australian men are undergoing treatment for localized prostate cancer (PCa), the health-related quality of life (HRQOL) of this patient cohort has received little research attention. We therefore compared the mood and general HRQOL of Australian localized PCa patients with a sample of untreated men. METHODS: A retrospective cross-sectional design was used to compare the longer-term positive and negative affect and general HRQOL of 82 radical prostatectomy (RP) cases, 39 external-beam radiation (EBRT), and 95 untreated comparison cases (CC). All PCa cases had undergone treatment more than 2 years prior to data collection. RESULTS: Levels of positive and negative affect did not differ with treatment modality. After adjusting for the variance attributable to age and comorbidity, RP, EBRT and CC group participants displayed similar general HRQOL profiles. Treatment dissatisfaction was higher among EBRT compared to RP cases (P = 0.024, two-tailed test). CONCLUSION: In the longer-term, mood did not vary significantly with PCa treatment. Furthermore, when age and comorbidity were taken into account, RP and EBRT patients had similar HRQOL profiles. While not statistically significant, the trend towards the importance of family, social and medical support among PCa patients requires further investigation.

AB - OBJECTIVE: Although increasing numbers of Australian men are undergoing treatment for localized prostate cancer (PCa), the health-related quality of life (HRQOL) of this patient cohort has received little research attention. We therefore compared the mood and general HRQOL of Australian localized PCa patients with a sample of untreated men. METHODS: A retrospective cross-sectional design was used to compare the longer-term positive and negative affect and general HRQOL of 82 radical prostatectomy (RP) cases, 39 external-beam radiation (EBRT), and 95 untreated comparison cases (CC). All PCa cases had undergone treatment more than 2 years prior to data collection. RESULTS: Levels of positive and negative affect did not differ with treatment modality. After adjusting for the variance attributable to age and comorbidity, RP, EBRT and CC group participants displayed similar general HRQOL profiles. Treatment dissatisfaction was higher among EBRT compared to RP cases (P = 0.024, two-tailed test). CONCLUSION: In the longer-term, mood did not vary significantly with PCa treatment. Furthermore, when age and comorbidity were taken into account, RP and EBRT patients had similar HRQOL profiles. While not statistically significant, the trend towards the importance of family, social and medical support among PCa patients requires further investigation.

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