Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome

Nora Straznicky; Mariee Grima; Elisabeth Lambert; Carolina I Sari; Nina Eikelis; Paul John Nestel; Sarah E Phillips; Dagmara Hering; Sofie Karapanagiotidis; John Dixon; Markus Peter Schlaich; Gavin William Lambert

doi:10.1210/jc.2014-3796

Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome

Nora Straznicky, Mariee Grima, Elisabeth Lambert, Carolina I Sari, Nina Eikelis, Paul John Nestel, Sarah E Phillips, Dagmara Hering, Sofie Karapanagiotidis, John Dixon, Markus Peter Schlaich, Gavin William Lambert

Research output: Contribution to journal › Article › Research › peer-review

14 Citations (Scopus)

Abstract

Impaired insulin clearance contributes to the hyperinsulinemia of obesity, yet relatively little is known concerning the pathophysiological determinants of insulin clearance in obese populations. The objective of this paper is to examine the cross-sectional relationship between insulin clearance and resting sympathetic nervous system activity in a cohort of obese subjects with metabolic syndrome.

Original language	English
Pages (from-to)	1544 - 1550
Number of pages	7
Journal	The Journal of Clinical Endocrinology & Metabolism
Volume	100
Issue number	4
DOIs	https://doi.org/10.1210/jc.2014-3796
Publication status	Published - 2015

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10.1210/jc.2014-3796

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Straznicky, N., Grima, M., Lambert, E., Sari, C. I., Eikelis, N., Nestel, P. J., Phillips, S. E., Hering, D., Karapanagiotidis, S., Dixon, J., Schlaich, M. P., & Lambert, G. W. (2015). Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome. The Journal of Clinical Endocrinology & Metabolism, 100(4), 1544 - 1550. https://doi.org/10.1210/jc.2014-3796

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abstract = "Impaired insulin clearance contributes to the hyperinsulinemia of obesity, yet relatively little is known concerning the pathophysiological determinants of insulin clearance in obese populations. The objective of this paper is to examine the cross-sectional relationship between insulin clearance and resting sympathetic nervous system activity in a cohort of obese subjects with metabolic syndrome.",

author = "Nora Straznicky and Mariee Grima and Elisabeth Lambert and Sari, {Carolina I} and Nina Eikelis and Nestel, {Paul John} and Phillips, {Sarah E} and Dagmara Hering and Sofie Karapanagiotidis and John Dixon and Schlaich, {Markus Peter} and Lambert, {Gavin William}",

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language = "English",

volume = "100",

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Straznicky, N, Grima, M, Lambert, E, Sari, CI, Eikelis, N, Nestel, PJ, Phillips, SE, Hering, D, Karapanagiotidis, S, Dixon, J, Schlaich, MP & Lambert, GW 2015, 'Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome', The Journal of Clinical Endocrinology & Metabolism, vol. 100, no. 4, pp. 1544 - 1550. https://doi.org/10.1210/jc.2014-3796

Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome. / Straznicky, Nora; Grima, Mariee; Lambert, Elisabeth et al.
In: The Journal of Clinical Endocrinology & Metabolism, Vol. 100, No. 4, 2015, p. 1544 - 1550.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome

AU - Straznicky, Nora

AU - Grima, Mariee

AU - Lambert, Elisabeth

AU - Sari, Carolina I

AU - Eikelis, Nina

AU - Nestel, Paul John

AU - Phillips, Sarah E

AU - Hering, Dagmara

AU - Karapanagiotidis, Sofie

AU - Dixon, John

AU - Schlaich, Markus Peter

AU - Lambert, Gavin William

PY - 2015

Y1 - 2015

N2 - Impaired insulin clearance contributes to the hyperinsulinemia of obesity, yet relatively little is known concerning the pathophysiological determinants of insulin clearance in obese populations. The objective of this paper is to examine the cross-sectional relationship between insulin clearance and resting sympathetic nervous system activity in a cohort of obese subjects with metabolic syndrome.

AB - Impaired insulin clearance contributes to the hyperinsulinemia of obesity, yet relatively little is known concerning the pathophysiological determinants of insulin clearance in obese populations. The objective of this paper is to examine the cross-sectional relationship between insulin clearance and resting sympathetic nervous system activity in a cohort of obese subjects with metabolic syndrome.

UR - http://press.endocrine.org/doi/pdf/10.1210/jc.2014-3796

U2 - 10.1210/jc.2014-3796

DO - 10.1210/jc.2014-3796

M3 - Article

SN - 0021-972X

VL - 100

SP - 1544

EP - 1550

JO - The Journal of Clinical Endocrinology & Metabolism

JF - The Journal of Clinical Endocrinology & Metabolism

IS - 4

ER -

Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome

Abstract

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