Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome

Nora Straznicky, Mariee Grima, Elisabeth Lambert, Carolina I Sari, Nina Eikelis, Paul John Nestel, Sarah E Phillips, Dagmara Hering, Sofie Karapanagiotidis, John Dixon, Markus Peter Schlaich, Gavin William Lambert

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12 Citations (Scopus)

Abstract

Impaired insulin clearance contributes to the hyperinsulinemia of obesity, yet relatively little is known concerning the pathophysiological determinants of insulin clearance in obese populations. The objective of this paper is to examine the cross-sectional relationship between insulin clearance and resting sympathetic nervous system activity in a cohort of obese subjects with metabolic syndrome.
Original languageEnglish
Pages (from-to)1544 - 1550
Number of pages7
JournalThe Journal of Clinical Endocrinology and Metabolism
Volume100
Issue number4
DOIs
Publication statusPublished - 2015

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