Are branched chain fatty acids the natural substrates for P450 BM3?

Max J. Cryle, Rocio D. Espinoza, Sarah J. Smith, Nicholas J. Matovic, James J. De Voss

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Abstract

Branched chain fatty acids are substrates for cytochrome P450BM3 (CYP102) from Bacillus megaterium; oxidation of C15 and C 17 iso and anteiso fatty acids by P450BM3 leads to the formation of hydroxylated products that possess high levels of regiochemical and stereochemical purity.

Original languageEnglish
Pages (from-to)2353-2355
Number of pages3
JournalChemical Communications
Issue number22
DOIs
Publication statusPublished - 2006
Externally publishedYes

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