Aquagenic pruritus induced by clomipramine

Mauro Vitor Mendlowicz, João Luiz Lopes Lima, Leonardo Franklin Fontenelle

Research output: Contribution to journalComment / DebateOtherpeer-review

6 Citations (Scopus)


Objective: Aquagenic pruritus is the development of severe, prickling-like skin discomfort without observable skin lesions that is evoked by contact with water at any temperature. Method: This is a case report of a man presenting with aquagenic pruritus after starting clomipramine treatment for anxiety and depression. Results: The patient's aquagenic pruritus resolved after discontinuing the clomipramine but reemerged when treatment was restarted. Conclusions: A greater awareness and knowledge about aquagenic pruritus among physicians could help improve the clinical recognition and management of this clinical entity.

Original languageEnglish
JournalGeneral Hospital Psychiatry
Issue number5
Publication statusPublished - Sept 2013
Externally publishedYes


  • Adverse effects
  • Antidepressive agents
  • Clomipramine
  • Pruritus
  • Skin diseases

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