Applications of monolithic materials for sample preparation

Tarang Nema, Eric C.Y. Chan, Paul C. Ho

Research output: Contribution to journalReview ArticleResearchpeer-review

68 Citations (Scopus)

Abstract

Recent advances in monolithic columns have made them an alternative to traditional packed columns used in liquid chromatography as well as capillary electrochromatography (CEC). The monolithic columns have been extensively studied and shown to possess several advantages that make them a promising and potential substitute for the particle packed columns. A large number of papers relating to monolithic columns have been published every year, focusing on different preparation techniques, characteristic evaluations as well as applications. This review highlighted the latest development of monoliths for other modes of analytical chemistry. In particular, this review will highlight the application of monoliths for sample preparation which is an important step of the entire analysis.

Original languageEnglish
Pages (from-to)130-141
Number of pages12
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume87
DOIs
Publication statusPublished - 18 Jan 2014
Externally publishedYes

Keywords

  • Capillary columns
  • Monolithic columns
  • Organic-inorganic monoliths
  • Solid-phase extraction
  • Stationary phases

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