TY - JOUR
T1 - Applications of conducting polymers and their issues in biomedical engineering
AU - Ravichandran, Rajeswari
AU - Sundarrajan, Subramanian
AU - Venugopal, Jayarama Reddy
AU - Mukherjee, Shayanti
AU - Ramakrishna, Seeram
PY - 2010/10/6
Y1 - 2010/10/6
N2 - Conducting polymers (CPs) have attracted much interest as suitable matrices of biomolecules and have been used to enhance the stability, speed and sensitivity of various biomedical devices. Moreover, CPs are inexpensive, easy to synthesize and versatile because their properties can be readily modulated by (i) surface functionalization techniques and (ii) the use of a wide range of molecules that can be entrapped or used as dopants. This paper discusses the various surface modifications of the CP that can be employed in order to impart physico-chemical and biological guidance cues that promote cell adhesion/proliferation at the polymer-tissue interface. This ability of the CP to induce various cellular mechanisms widens its applications in medical fields and bioengineering.
AB - Conducting polymers (CPs) have attracted much interest as suitable matrices of biomolecules and have been used to enhance the stability, speed and sensitivity of various biomedical devices. Moreover, CPs are inexpensive, easy to synthesize and versatile because their properties can be readily modulated by (i) surface functionalization techniques and (ii) the use of a wide range of molecules that can be entrapped or used as dopants. This paper discusses the various surface modifications of the CP that can be employed in order to impart physico-chemical and biological guidance cues that promote cell adhesion/proliferation at the polymer-tissue interface. This ability of the CP to induce various cellular mechanisms widens its applications in medical fields and bioengineering.
KW - Biomedical devices
KW - Biomedical engineering
KW - Conducting polymers
UR - http://www.scopus.com/inward/record.url?scp=77957164515&partnerID=8YFLogxK
U2 - 10.1098/rsif.2010.0120.focus
DO - 10.1098/rsif.2010.0120.focus
M3 - Review Article
AN - SCOPUS:77957164515
VL - 7
SP - S559-S579
JO - Journal of the Royal Society Interface
JF - Journal of the Royal Society Interface
SN - 1742-5689
IS - SUPPL. 5
ER -