TY - JOUR
T1 - Application of microscale-preparative multidimensional gas chromatography with nuclear magnetic resonance spectroscopy for identification of pure methylnaphthalenes from crude oils
AU - Eyres, Graham
AU - Urban, Sylvia
AU - Morrison, Paul
AU - Marriott, Philip
PY - 2008
Y1 - 2008
N2 - Mass spectrometry is often insufficient to distinguish between structural isomers, requiring confirmation using NMR spectroscopy. Here, a novel preparative technique based upon capillary multidimensional gas chromatography to isolate pure volatile components from complex samples is described. The method was developed through isolation of 1,4-dimethoxybenzene (5.2 mu g. 10 injections) from a peppermint essential oil. Then isomers of 1- and 2-methylnaphthalene were isolated from a complex crude oil in sufficient amounts (3.1 mu g, 38 injections and 5.0 mu g, 35 injections) for discrimination using (1)H NMR spectroscopy. This methodology is applicable to identify any volatile molecule in complex matrices requiring confirmation using NMR spectroscopy.
AB - Mass spectrometry is often insufficient to distinguish between structural isomers, requiring confirmation using NMR spectroscopy. Here, a novel preparative technique based upon capillary multidimensional gas chromatography to isolate pure volatile components from complex samples is described. The method was developed through isolation of 1,4-dimethoxybenzene (5.2 mu g. 10 injections) from a peppermint essential oil. Then isomers of 1- and 2-methylnaphthalene were isolated from a complex crude oil in sufficient amounts (3.1 mu g, 38 injections and 5.0 mu g, 35 injections) for discrimination using (1)H NMR spectroscopy. This methodology is applicable to identify any volatile molecule in complex matrices requiring confirmation using NMR spectroscopy.
UR - http://www.sciencedirect.com.ezproxy.lib.monash.edu.au/science/article/pii/S0021967308019286
U2 - 10.1016/j.chroma.2008.10.102
DO - 10.1016/j.chroma.2008.10.102
M3 - Article
SN - 0021-9673
VL - 1215
SP - 168
EP - 176
JO - Journal of Chromatography A
JF - Journal of Chromatography A
IS - 1-2
ER -