Application of gold nanoparticles embedded in the amyloids fibrils as enhancers in the laser induced breakdown spectroscopy for the metal quantification in microdroplets

Marcella Dell'Aglio, Zita Salajková, Antonia Mallardi, Raffaele Mezzenga, Leonie van't Hag, Nicola Cioffi, Gerardo Palazzo, Alessandro De Giacomo

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15 Citations (Scopus)

Abstract

In this work Nanoparticle Enhanced Laser Induced Breakdown Spectroscopy (NELIBS) has been employed for quantitative metal detection using amyloid fibrils coated with gold nanoparticles as enhancers. Amyloid fibrils represent, from one hand, an extremely interesting system for novel technologies, ranging from water purification to medical applications, and on the other hand, an ideal system for investigating the performance of laser-matter interaction in biological systems. The results obtained in this work show the potentiality of NELIBS for the quantification at sub-ppm (mg/kg) level of metallic elements (Cr, Pb, Tl and Cd) even in the protein and/or biological environment, employing amyloid fibrils with gold nanoparticles. Moreover, the single-shot measurements reveal the promising use of this technique in applications where high sensitivity and/or limitation in the sample amount are demanded.

Original languageEnglish
Pages (from-to)115-122
Number of pages8
JournalSpectrochimica Acta, Part B: Atomic Spectroscopy
Volume155
DOIs
Publication statusPublished - May 2019
Externally publishedYes

Keywords

  • Amyloids fibrils
  • Gold nanoparticles
  • Micro-droplets
  • Nanoparticle enhanced LIBS
  • Trace elements

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