Application of C18-Modified Mseoporous SBA-15 as the Substrate for High Performance Liquid Chromatography

Feng Gao; Jian Wei Zhao; Song Zhang; Feng Zhou; Wan Jin; Xiang Min Zhang; Peng Yuan Yang; Dong Yuan Zhao

Application of C₁₈-Modified Mseoporous SBA-15 as the Substrate for High Performance Liquid Chromatography

Feng Gao, Jian Wei Zhao, Song Zhang, Feng Zhou, Wan Jin, Xiang Min Zhang, Peng Yuan Yang, Dong Yuan Zhao

Research output: Contribution to journal › Article › Research › peer-review

Abstract

C₁₈ functionalized mesoporous silica SBA-15 with a high surface area was applied in high performance liquid chromatography (HPLC) to separate small biomolecules: cysteine, glutathione, dopamine and 6-thiopurine. Compared to commercial available C₁₈ column, C₁₈-SBA-15 has a much higher surface area, which enhances the capillary HPLC resolution by increasing molecular capacity factors. The uniform distributed mesopores in SBA-15 result in HPLC peaks narrower than that of commercial column. Mesoporous SBA-15 can be used as an excellent HPLC stationary phase for special applications for its low cost, easy synthesis and various group-modifications.

Original language	English
Number of pages	1
Journal	Chemical Journal of Chinese Universities
Volume	23
Issue number	8
Publication status	Published - 1 Aug 2002
Externally published	Yes

Keywords

HPLC
Mercapto compound
Mesoporous silica
SBA-15

Cite this

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title = "Application of C18-Modified Mseoporous SBA-15 as the Substrate for High Performance Liquid Chromatography",

abstract = "C18 functionalized mesoporous silica SBA-15 with a high surface area was applied in high performance liquid chromatography (HPLC) to separate small biomolecules: cysteine, glutathione, dopamine and 6-thiopurine. Compared to commercial available C18 column, C18-SBA-15 has a much higher surface area, which enhances the capillary HPLC resolution by increasing molecular capacity factors. The uniform distributed mesopores in SBA-15 result in HPLC peaks narrower than that of commercial column. Mesoporous SBA-15 can be used as an excellent HPLC stationary phase for special applications for its low cost, easy synthesis and various group-modifications.",

keywords = "HPLC, Mercapto compound, Mesoporous silica, SBA-15",

author = "Feng Gao and Zhao, {Jian Wei} and Song Zhang and Feng Zhou and Wan Jin and Zhang, {Xiang Min} and Yang, {Peng Yuan} and Zhao, {Dong Yuan}",

year = "2002",

month = aug,

day = "1",

language = "English",

volume = "23",

journal = "Chemical Journal of Chinese Universities",

issn = "0251-0790",

publisher = "Jilin University",

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TY - JOUR

T1 - Application of C18-Modified Mseoporous SBA-15 as the Substrate for High Performance Liquid Chromatography

AU - Gao, Feng

AU - Zhao, Jian Wei

AU - Zhang, Song

AU - Zhou, Feng

AU - Jin, Wan

AU - Zhang, Xiang Min

AU - Yang, Peng Yuan

AU - Zhao, Dong Yuan

PY - 2002/8/1

Y1 - 2002/8/1

N2 - C18 functionalized mesoporous silica SBA-15 with a high surface area was applied in high performance liquid chromatography (HPLC) to separate small biomolecules: cysteine, glutathione, dopamine and 6-thiopurine. Compared to commercial available C18 column, C18-SBA-15 has a much higher surface area, which enhances the capillary HPLC resolution by increasing molecular capacity factors. The uniform distributed mesopores in SBA-15 result in HPLC peaks narrower than that of commercial column. Mesoporous SBA-15 can be used as an excellent HPLC stationary phase for special applications for its low cost, easy synthesis and various group-modifications.

AB - C18 functionalized mesoporous silica SBA-15 with a high surface area was applied in high performance liquid chromatography (HPLC) to separate small biomolecules: cysteine, glutathione, dopamine and 6-thiopurine. Compared to commercial available C18 column, C18-SBA-15 has a much higher surface area, which enhances the capillary HPLC resolution by increasing molecular capacity factors. The uniform distributed mesopores in SBA-15 result in HPLC peaks narrower than that of commercial column. Mesoporous SBA-15 can be used as an excellent HPLC stationary phase for special applications for its low cost, easy synthesis and various group-modifications.

KW - HPLC

KW - Mercapto compound

KW - Mesoporous silica

KW - SBA-15

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M3 - Article

AN - SCOPUS:0347899593

SN - 0251-0790

VL - 23

JO - Chemical Journal of Chinese Universities

JF - Chemical Journal of Chinese Universities

IS - 8

ER -

Application of C18-Modified Mseoporous SBA-15 as the Substrate for High Performance Liquid Chromatography

Abstract

Keywords

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Cite this

Application of C₁₈-Modified Mseoporous SBA-15 as the Substrate for High Performance Liquid Chromatography