Application of a new nucleophilic addition/ring closure (NARC) sequence to the synthesis of enantiomerically-pure 2,8-dioxabicyclo[3.2.1]octanes of relevance to the squalestatins and zaragozic acids

Gary D Fallon, Eric Dale Jones, Patrick Perlmutter, Walailak Selajarern

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16 Citations (Scopus)


A rapid method for the enantioselective construction of 2,8-dioxabicyclo[3.2.1]octanes of relevance to the zaragozic acids, employing a tandem NARC sequence of aldol and intramol. Wacker reactions, is described. [on SciFinder(R)]
Original languageEnglish
Pages (from-to)7435 - 7438
Number of pages4
JournalTetrahedron Letters
Issue number41
Publication statusPublished - 1999

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