Aortic intima-media thickness measured by trans-abdominal ultrasound as an early life marker of subclinical atherosclerosis

Kate McCloskey, Peter Vuillermin, Anne-Louise Ponsonby, Michael Cheung, Michael R Skilton, David Burgner

Research output: Contribution to journalReview ArticleResearchpeer-review

20 Citations (Scopus)

Abstract

Atherosclerosis is a chronic inflammatory process that begins in early life. Improved identification of markers of early atherosclerosis via neonatal aortic intima-media thickness (aIMT) measurement may allow the development of interventions to prevent or reduce later cardiovascular disease. Conclusion Using aIMT, studies have shown that antenatal factors such as intra-uterine growth retardation, prematurity, maternal factors and inflammation are associated with early cardiovascular changes.

Original languageEnglish
Pages (from-to)124-130
Number of pages7
JournalActa Paediatrica
Volume103
Issue number2
DOIs
Publication statusPublished - Feb 2014
Externally publishedYes

Keywords

  • Aorta
  • Atherosclerosis
  • Cardiovascular
  • Intima-media
  • Neonatal

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